Toda M - Search Results

1

Discovery of selective indole-based prostaglandin D₂ receptor antagonist.

Iwahashi M, Shimabukuro A, Onoda T, Matsunaga Y, Okada Y, Matsumoto R, Nambu F, Nakai H, Toda M. Iwahashi M, et al. Among authors: toda m. Bioorg Med Chem. 2011 Aug 1;19(15):4574-88. doi: 10.1016/j.bmc.2011.06.014. Epub 2011 Jun 16. Bioorg Med Chem. 2011. PMID: 21737285

2

Design and synthesis of a selective EP4-receptor agonist. Part 1: discovery of 3,7-dithiaPGE1 derivatives and identification of their omega chains.

Maruyama T, Asada M, Shiraishi T, Egashira H, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: toda m. Bioorg Med Chem. 2002 Apr;10(4):975-88. doi: 10.1016/s0968-0896(01)00351-0. Bioorg Med Chem. 2002. PMID: 11836107

3

Development of a highly selective EP2-receptor agonist. Part 1: identification of 16-hydroxy-17,17-trimethylene PGE2 derivatives.

Tani K, Naganawa A, Ishida A, Sagawa K, Harada H, Ogawa M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Tani K, et al. Among authors: toda m. Bioorg Med Chem. 2002 Apr;10(4):1093-106. doi: 10.1016/s0968-0896(01)00369-8. Bioorg Med Chem. 2002. PMID: 11836120

4

Design and synthesis of a selective EP4-receptor agonist. Part 3: 16-phenyl-5-thiaPGE(1) and 9-beta-halo derivatives with improved stability.

Maruyama T, Asada M, Shiraishi T, Yoshida H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Maruyama T, et al. Among authors: toda m. Bioorg Med Chem. 2002 Jun;10(6):1743-59. doi: 10.1016/s0968-0896(02)00031-7. Bioorg Med Chem. 2002. PMID: 11937333

5

Discovery of orally active prostaglandin D2 receptor antagonists.

Torisu K, Kobayashi K, Iwahashi M, Nakai Y, Onoda T, Nagase T, Sugimoto I, Okada Y, Matsumoto R, Nanbu F, Ohuchida S, Nakai H, Toda M. Torisu K, et al. Among authors: toda m. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4891-5. doi: 10.1016/j.bmcl.2004.07.039. Bioorg Med Chem Lett. 2004. PMID: 15341946

6

Discovery of new chemical leads for prostaglandin D2 receptor antagonists.

Torisu K, Kobayashi K, Iwahashi M, Egashira H, Nakai Y, Okada Y, Nanbu F, Ohuchida S, Nakai H, Toda M. Torisu K, et al. Among authors: toda m. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4557-62. doi: 10.1016/j.bmcl.2004.06.006. Bioorg Med Chem Lett. 2004. PMID: 15357992

7

Discovery of a new class of potent, selective, and orally active prostaglandin D2 receptor antagonists.

Torisu K, Kobayashi K, Iwahashi M, Nakai Y, Onoda T, Nagase T, Sugimoto I, Okada Y, Matsumoto R, Nanbu F, Ohuchida S, Nakai H, Toda M. Torisu K, et al. Among authors: toda m. Bioorg Med Chem. 2004 Oct 15;12(20):5361-78. doi: 10.1016/j.bmc.2004.07.048. Bioorg Med Chem. 2004. PMID: 15388164

8

Development of a prostaglandin D2 receptor antagonist: discovery of a new chemical lead.

Torisu K, Kobayashi K, Iwahashi M, Egashira H, Nakai Y, Okada Y, Nanbu F, Ohuchida S, Nakai H, Toda M. Torisu K, et al. Among authors: toda m. Eur J Med Chem. 2005 May;40(5):505-19. doi: 10.1016/j.ejmech.2004.11.011. Eur J Med Chem. 2005. PMID: 15893024

9

Discovery of new chemical leads for selective EP1 receptor antagonists.

Naganawa A, Saito T, Nagao Y, Egashira H, Iwahashi M, Kambe T, Koketsu M, Yamamoto H, Kobayashi M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Naganawa A, et al. Among authors: toda m. Bioorg Med Chem. 2006 Aug 15;14(16):5562-77. doi: 10.1016/j.bmc.2006.04.038. Epub 2006 May 12. Bioorg Med Chem. 2006. PMID: 16697646

10

Discovery of heteroaryl sulfonamides as new EP1 receptor selective antagonists.

Naganawa A, Matsui T, Saito T, Ima M, Tatsumi T, Yamamoto S, Murota M, Yamamoto H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Naganawa A, et al. Among authors: toda m. Bioorg Med Chem. 2006 Oct 1;14(19):6628-39. doi: 10.1016/j.bmc.2006.05.076. Epub 2006 Jun 19. Bioorg Med Chem. 2006. PMID: 16784865

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