Tofaris GK - Search Results

1

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome.

Tofaris GK, Layfield R, Spillantini MG. Tofaris GK, et al. FEBS Lett. 2001 Nov 30;509(1):22-6. doi: 10.1016/s0014-5793(01)03115-5. FEBS Lett. 2001. PMID: 11734199 Free article.

2

Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function.

Tofaris GK, Razzaq A, Ghetti B, Lilley KS, Spillantini MG. Tofaris GK, et al. J Biol Chem. 2003 Nov 7;278(45):44405-11. doi: 10.1074/jbc.M308041200. Epub 2003 Aug 15. J Biol Chem. 2003. PMID: 12923179 Free article.

3

Alpha-synuclein dysfunction in Lewy body diseases.

Tofaris GK, Spillantini MG. Tofaris GK, et al. Mov Disord. 2005 Aug;20 Suppl 12:S37-44. doi: 10.1002/mds.20538. Mov Disord. 2005. PMID: 16092089

4

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

Tofaris GK, Garcia Reitböck P, Humby T, Lambourne SL, O'Connell M, Ghetti B, Gossage H, Emson PC, Wilkinson LS, Goedert M, Spillantini MG. Tofaris GK, et al. J Neurosci. 2006 Apr 12;26(15):3942-50. doi: 10.1523/JNEUROSCI.4965-05.2006. J Neurosci. 2006. PMID: 16611810 Free PMC article.

5

Physiological and pathological properties of alpha-synuclein.

Tofaris GK, Spillantini MG. Tofaris GK, et al. Cell Mol Life Sci. 2007 Sep;64(17):2194-201. doi: 10.1007/s00018-007-7217-5. Cell Mol Life Sci. 2007. PMID: 17605001 Review.

6

The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease.

Michell AW, Tofaris GK, Gossage H, Tyers P, Spillantini MG, Barker RA. Michell AW, et al. Among authors: tofaris gk. Cell Transplant. 2007;16(5):461-74. doi: 10.3727/000000007783464911. Cell Transplant. 2007. PMID: 17708336 Free article.

7

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease.

Garcia-Reitböck P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, Ghetti B, Della Corte L, Spano P, Tofaris GK, Goedert M, Spillantini MG. Garcia-Reitböck P, et al. Among authors: tofaris gk. Brain. 2010 Jul;133(Pt 7):2032-44. doi: 10.1093/brain/awq132. Epub 2010 Jun 9. Brain. 2010. PMID: 20534649 Free PMC article.

8

Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra.

Garcia-Reitboeck P, Anichtchik O, Dalley JW, Ninkina N, Tofaris GK, Buchman VL, Spillantini MG. Garcia-Reitboeck P, et al. Among authors: tofaris gk. Exp Neurol. 2013 Oct;248:541-5. doi: 10.1016/j.expneurol.2013.07.015. Epub 2013 Aug 8. Exp Neurol. 2013. PMID: 23933574 Free PMC article.

9

The Transcellular Propagation and Intracellular Trafficking of α-Synuclein.

Tofaris GK, Goedert M, Spillantini MG. Tofaris GK, et al. Cold Spring Harb Perspect Med. 2017 Sep 1;7(9):a024380. doi: 10.1101/cshperspect.a024380. Cold Spring Harb Perspect Med. 2017. PMID: 27920026 Free PMC article. Review.

10

How is alpha-synuclein cleared from the cell?

Stefanis L, Emmanouilidou E, Pantazopoulou M, Kirik D, Vekrellis K, Tofaris GK. Stefanis L, et al. Among authors: tofaris gk. J Neurochem. 2019 Sep;150(5):577-590. doi: 10.1111/jnc.14704. Epub 2019 May 8. J Neurochem. 2019. PMID: 31069800 Free article. Review.

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