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The role of UGT1A1*28 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer.
Toffoli G, Cecchin E, Corona G, Russo A, Buonadonna A, D'Andrea M, Pasetto LM, Pessa S, Errante D, De Pangher V, Giusto M, Medici M, Gaion F, Sandri P, Galligioni E, Bonura S, Boccalon M, Biason P, Frustaci S. Toffoli G, et al. J Clin Oncol. 2006 Jul 1;24(19):3061-8. doi: 10.1200/JCO.2005.05.5400. J Clin Oncol. 2006. PMID: 16809730 Clinical Trial.
Innovative schedule of oral idarubicin in elderly patients with metastatic breast cancer: comprehensive results of a phase II multi-institutional study with pharmacokinetic drug monitoring.
Crivellari D, Lombardi D, Corona G, Massacesi C, Talamini R, Sorio R, Magri MD, Lestuzzi C, Lucenti A, Veronesi A, Toffoli G. Crivellari D, et al. Among authors: toffoli g. Ann Oncol. 2006 May;17(5):807-12. doi: 10.1093/annonc/mdl013. Epub 2006 Feb 23. Ann Oncol. 2006. PMID: 16497825 Clinical Trial.
Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer.
Toffoli G, Cecchin E, Gasparini G, D'Andrea M, Azzarello G, Basso U, Mini E, Pessa S, De Mattia E, Lo Re G, Buonadonna A, Nobili S, De Paoli P, Innocenti F. Toffoli G, et al. J Clin Oncol. 2010 Feb 10;28(5):866-71. doi: 10.1200/JCO.2009.23.6125. Epub 2009 Dec 28. J Clin Oncol. 2010. PMID: 20038727 Free PMC article. Clinical Trial.
Standard fluoropyrimidine dosages in chemoradiation therapy result in an increased risk of severe toxicity in DPYD variant allele carriers.
Lunenburg CATC, Henricks LM, Dreussi E, Peters FP, Fiocco M, Meulendijks D, Toffoli G, Guchelaar HJ, Swen JJ, Cecchin E, Schellens JHM, Gelderblom H. Lunenburg CATC, et al. Among authors: toffoli g. Eur J Cancer. 2018 Nov;104:210-218. doi: 10.1016/j.ejca.2018.07.138. Epub 2018 Oct 23. Eur J Cancer. 2018. PMID: 30361102
Sarcomas and pharmacogenetics.
Biason P, Toffoli G. Biason P, et al. Among authors: toffoli g. Pharmacogenomics. 2005 Sep;6(6):585-601. doi: 10.2217/14622416.6.6.585. Pharmacogenomics. 2005. PMID: 16142999 Review.
297 results