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The bronchodilatory effect of deep inspiration diminishes with aging.
Scichilone N, Marchese R, Catalano F, Togias A, Vignola AM, Bellia V. Scichilone N, et al. Among authors: togias a. Respir Med. 2004 Sep;98(9):838-43. doi: 10.1016/j.rmed.2004.02.023. Respir Med. 2004. PMID: 15338795
Should atopy be assessed in elderly patients with respiratory symptoms suggestive of asthma?
Scichilone N, Augugliaro G, Togias A, Bellia V. Scichilone N, et al. Among authors: togias a. Expert Rev Respir Med. 2010 Oct;4(5):585-91. doi: 10.1586/ers.10.55. Expert Rev Respir Med. 2010. PMID: 20923338 Review.
Aging is associated with modifications of the immune system and this could contribute to a reduced prevalence of allergic disease in the elderly. ...This article is a review of the available literature assessing the impact of age on atopy in the asthmatic patient. I …
Aging is associated with modifications of the immune system and this could contribute to a reduced prevalence of allergic disease in …
The impact of age on prevalence of positive skin prick tests and specific IgE tests.
Scichilone N, Callari A, Augugliaro G, Marchese M, Togias A, Bellia V. Scichilone N, et al. Among authors: togias a. Respir Med. 2011 May;105(5):651-8. doi: 10.1016/j.rmed.2010.12.014. Epub 2011 Jan 8. Respir Med. 2011. PMID: 21220195 Review.
This article is a review of the available literature assessing the impact of age on atopy. In the majority of papers, we found a lower prevalence of atopy in the most advanced ages, both in healthy subjects and in individuals affected by allergic respiratory disease …
This article is a review of the available literature assessing the impact of age on atopy. In the majority of papers, we found a
The bronchoprotective effect of deep inspiration is flow rate dependent.
Skloot GS, Chandy D, Schachter N, Togias A. Skloot GS, et al. Among authors: togias a. Respir Med. 2007 Jul;101(7):1376-82. doi: 10.1016/j.rmed.2007.02.001. Epub 2007 Mar 26. Respir Med. 2007. PMID: 17379494
SETTING: Pulmonary function laboratory within a large tertiary medical center. PARTICIPANTS: Ten healthy nonsmokers without asthma or rhinitis. ...CONCLUSION: A fast DI is bronchoprotective while a slow DI is not. Elucidating the conditions that maximize or a …
SETTING: Pulmonary function laboratory within a large tertiary medical center. PARTICIPANTS: Ten healthy nonsmokers without asthma or …
Impaired response to deep inspiration in obesity.
Skloot G, Schechter C, Desai A, Togias A. Skloot G, et al. Among authors: togias a. J Appl Physiol (1985). 2011 Sep;111(3):726-34. doi: 10.1152/japplphysiol.01155.2010. Epub 2011 Jun 23. J Appl Physiol (1985). 2011. PMID: 21700888 Free PMC article.
Thirty-six subjects (17 obese, 19 nonobese) underwent routine methacholine (Mch) challenge and 30 of them also had a modified bronchoprovocation in the absence of DIs. ...We conclude that obesity is characterized by increased Mch responsiveness, predominantly of the small …
Thirty-six subjects (17 obese, 19 nonobese) underwent routine methacholine (Mch) challenge and 30 of them also had a modified broncho …
Bronchodilation response to deep inspirations in asthma is dependent on airway distensibility and air trapping.
Pyrgos G, Scichilone N, Togias A, Brown RH. Pyrgos G, et al. Among authors: togias a. J Appl Physiol (1985). 2011 Feb;110(2):472-9. doi: 10.1152/japplphysiol.00603.2010. Epub 2010 Nov 11. J Appl Physiol (1985). 2011. PMID: 21071596 Free PMC article.
In healthy individuals, deep inspirations (DIs) have a potent bronchodilatory ability against methacholine (MCh)-induced bronchoconstriction. ...These relationships only exist in the presence of airway tone, indicating that structural changes in the conducting airways visu …
In healthy individuals, deep inspirations (DIs) have a potent bronchodilatory ability against methacholine (MCh)-induced bronchoconst …
Effects of exercise training on airway responsiveness and airway cells in healthy subjects.
Scichilone N, Morici G, Zangla D, Chimenti L, Davì E, Reitano S, Paternò A, Santagata R, Togias A, Bellia V, Bonsignore MR. Scichilone N, et al. Among authors: togias a. J Appl Physiol (1985). 2010 Aug;109(2):288-94. doi: 10.1152/japplphysiol.01200.2009. Epub 2010 Jun 10. J Appl Physiol (1985). 2010. PMID: 20538849
In this prospective study, we tested the hypothesis that a training exercise program reduces the bronchoconstrictive effect of Mch. ...Our data show that a course of exercise training can attenuate airway responsiveness against Mch inhaled in the absence of DIs in h …
In this prospective study, we tested the hypothesis that a training exercise program reduces the bronchoconstrictive effect of Mch. . …
The airway response to deep inspirations decreases with COPD severity and is associated with airway distensibility assessed by computed tomography.
Scichilone N, La Sala A, Bellia M, Fallano K, Togias A, Brown RH, Midiri M, Bellia V. Scichilone N, et al. Among authors: togias a. J Appl Physiol (1985). 2008 Sep;105(3):832-8. doi: 10.1152/japplphysiol.01307.2007. Epub 2008 Jul 10. J Appl Physiol (1985). 2008. PMID: 18617628 Free PMC article.
In this study, we tested the hypothesis that the effectiveness of DI is reduced with increasing disease severity and that this is associated with a reduction in the ability of DI to distend the airways. ...We found a strong correlation between the response to DI and …
In this study, we tested the hypothesis that the effectiveness of DI is reduced with increasing disease severity and that this is associated …
Alterations of the beneficial effect of deep inspiration in scleroderma: relationships between lung function and imaging.
Scichilone N, Reitano S, Bellia M, Riili M, Togias A, Midiri M, Triolo G, Bellia V. Scichilone N, et al. Among authors: togias a. Respiration. 2008;76(3):303-10. doi: 10.1159/000114148. Epub 2008 Jan 24. Respiration. 2008. PMID: 18216459
Deep inspiration-induced changes in lung volume decrease with severity of asthma.
Scichilone N, Marchese R, Soresi S, Interrante A, Togias A, Bellia V. Scichilone N, et al. Among authors: togias a. Respir Med. 2007 May;101(5):951-6. doi: 10.1016/j.rmed.2006.09.009. Epub 2006 Oct 17. Respir Med. 2007. PMID: 17049828
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