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A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.
Iyer LM, Nagarajan S, Woelfer M, Schoger E, Khadjeh S, Zafiriou MP, Kari V, Herting J, Pang ST, Weber T, Rathjens FS, Fischer TH, Toischer K, Hasenfuss G, Noack C, Johnsen SA, Zelarayán LC. Iyer LM, et al. Nucleic Acids Res. 2018 Apr 6;46(6):2850-2867. doi: 10.1093/nar/gky049. Nucleic Acids Res. 2018. PMID: 29394407 Free PMC article.
Impaired Ca(2+)-handling in HIF-1alpha(+/-) mice as a consequence of pressure overload.
Silter M, Kögler H, Zieseniss A, Wilting J, Schäfer K, Toischer K, Rokita AG, Breves G, Maier LS, Katschinski DM. Silter M, et al. Pflugers Arch. 2010 Mar;459(4):569-77. doi: 10.1007/s00424-009-0748-x. Epub 2009 Nov 8. Pflugers Arch. 2010. PMID: 19898976 Free PMC article.
Differential cardiac remodeling in preload versus afterload.
Toischer K, Rokita AG, Unsöld B, Zhu W, Kararigas G, Sossalla S, Reuter SP, Becker A, Teucher N, Seidler T, Grebe C, Preuss L, Gupta SN, Schmidt K, Lehnart SE, Krüger M, Linke WA, Backs J, Regitz-Zagrosek V, Schäfer K, Field LJ, Maier LS, Hasenfuss G. Toischer K, et al. Circulation. 2010 Sep 7;122(10):993-1003. doi: 10.1161/CIRCULATIONAHA.110.943431. Epub 2010 Aug 23. Circulation. 2010. PMID: 20733099 Free PMC article.
Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease.
Toischer K, Hartmann N, Wagner S, Fischer TH, Herting J, Danner BC, Sag CM, Hund TJ, Mohler PJ, Belardinelli L, Hasenfuss G, Maier LS, Sossalla S. Toischer K, et al. J Mol Cell Cardiol. 2013 Aug;61:111-22. doi: 10.1016/j.yjmcc.2013.03.021. Epub 2013 Apr 6. J Mol Cell Cardiol. 2013. PMID: 23570977 Free PMC article.
p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts.
Ongherth A, Pasch S, Wuertz CM, Nowak K, Kittana N, Weis CA, Jatho A, Vettel C, Tiburcy M, Toischer K, Hasenfuss G, Zimmermann WH, Wieland T, Lutz S. Ongherth A, et al. J Mol Cell Cardiol. 2015 Nov;88:39-54. doi: 10.1016/j.yjmcc.2015.09.009. Epub 2015 Sep 21. J Mol Cell Cardiol. 2015. PMID: 26392029
Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload.
Montes-Cobos E, Li X, Fischer HJ, Sasse A, Kügler S, Didié M, Toischer K, Fassnacht M, Dressel R, Reichardt HM. Montes-Cobos E, et al. PLoS One. 2015 Nov 25;10(11):e0143954. doi: 10.1371/journal.pone.0143954. eCollection 2015. PLoS One. 2015. PMID: 26605921 Free PMC article.
Molecular and structural transition mechanisms in long-term volume overload.
Mohamed BA, Schnelle M, Khadjeh S, Lbik D, Herwig M, Linke WA, Hasenfuss G, Toischer K. Mohamed BA, et al. Eur J Heart Fail. 2016 Apr;18(4):362-71. doi: 10.1002/ejhf.465. Epub 2015 Dec 23. Eur J Heart Fail. 2016. PMID: 26694078 Free PMC article.
Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome.
Dudek J, Cheng IF, Chowdhury A, Wozny K, Balleininger M, Reinhold R, Grunau S, Callegari S, Toischer K, Wanders RJ, Hasenfuß G, Brügger B, Guan K, Rehling P. Dudek J, et al. EMBO Mol Med. 2016 Feb 1;8(2):139-54. doi: 10.15252/emmm.201505644. EMBO Mol Med. 2016. PMID: 26697888 Free PMC article.
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