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Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose.
Toma L, Stancu CS, Botez GM, Sima AV, Simionescu M. Toma L, et al. Biochem Biophys Res Commun. 2009 Dec 18;390(3):877-82. doi: 10.1016/j.bbrc.2009.10.066. Epub 2009 Oct 20. Biochem Biophys Res Commun. 2009. PMID: 19850013
Anti-oxidant and anti-inflammatory mechanisms of amlodipine action to improve endothelial cell dysfunction induced by irreversibly glycated LDL.
Toma L, Stancu CS, Sanda GM, Sima AV. Toma L, et al. Biochem Biophys Res Commun. 2011 Jul 22;411(1):202-7. doi: 10.1016/j.bbrc.2011.06.137. Epub 2011 Jun 25. Biochem Biophys Res Commun. 2011. PMID: 21729693
Dual role of lipoproteins in endothelial cell dysfunction in atherosclerosis.
Stancu CS, Toma L, Sima AV. Stancu CS, et al. Among authors: toma l. Cell Tissue Res. 2012 Aug;349(2):433-46. doi: 10.1007/s00441-012-1437-1. Epub 2012 May 18. Cell Tissue Res. 2012. PMID: 22592627 Review.
Hyperlipidemia-induced hepatic and small intestine ER stress and decreased paraoxonase 1 expression and activity is associated with HDL dysfunction in Syrian hamsters.
Stancu CS, Carnuta MG, Sanda GM, Toma L, Deleanu M, Niculescu LS, Sasson S, Simionescu M, Sima AV. Stancu CS, et al. Among authors: toma l. Mol Nutr Food Res. 2015 Nov;59(11):2293-302. doi: 10.1002/mnfr.201500422. Epub 2015 Sep 13. Mol Nutr Food Res. 2015. PMID: 26304773
Glycated LDL increase VCAM-1 expression and secretion in endothelial cells and promote monocyte adhesion through mechanisms involving endoplasmic reticulum stress.
Toma L, Sanda GM, Deleanu M, Stancu CS, Sima AV. Toma L, et al. Mol Cell Biochem. 2016 Jun;417(1-2):169-79. doi: 10.1007/s11010-016-2724-z. Epub 2016 May 20. Mol Cell Biochem. 2016. PMID: 27206739
Oxidized LDL-Exposed Human Macrophages Display Increased MMP-9 Expression and Secretion Mediated by Endoplasmic Reticulum Stress.
Sanda GM, Deleanu M, Toma L, Stancu CS, Simionescu M, Sima AV. Sanda GM, et al. Among authors: toma l. J Cell Biochem. 2017 Apr;118(4):661-669. doi: 10.1002/jcb.25637. Epub 2016 Nov 28. J Cell Biochem. 2017. PMID: 27341688
Caffeic acid attenuates the inflammatory stress induced by glycated LDL in human endothelial cells by mechanisms involving inhibition of AGE-receptor, oxidative, and endoplasmic reticulum stress.
Toma L, Sanda GM, Niculescu LS, Deleanu M, Stancu CS, Sima AV. Toma L, et al. Biofactors. 2017 Sep 10;43(5):685-697. doi: 10.1002/biof.1373. Epub 2017 Jul 28. Biofactors. 2017. PMID: 28753257
Dysfunctional high-density lipoproteins have distinct composition, diminished anti-inflammatory potential and discriminate acute coronary syndrome from stable coronary artery disease patients.
Carnuta MG, Stancu CS, Toma L, Sanda GM, Niculescu LS, Deleanu M, Popescu AC, Popescu MR, Vlad A, Dimulescu DR, Simionescu M, Sima AV. Carnuta MG, et al. Among authors: toma l. Sci Rep. 2017 Aug 4;7(1):7295. doi: 10.1038/s41598-017-07821-5. Sci Rep. 2017. PMID: 28779156 Free PMC article.
Ninjurin-1 upregulated by TNFα receptor 1 stimulates monocyte adhesion to human TNFα-activated endothelial cells; benefic effects of amlodipine.
Toma L, Sanda GM, Raileanu M, Stancu CS, Niculescu LS, Sima AV. Toma L, et al. Life Sci. 2020 May 15;249:117518. doi: 10.1016/j.lfs.2020.117518. Epub 2020 Mar 6. Life Sci. 2020. PMID: 32147432
Phenolic Compounds Exerting Lipid-Regulatory, Anti-Inflammatory and Epigenetic Effects as Complementary Treatments in Cardiovascular Diseases.
Toma L, Sanda GM, Niculescu LS, Deleanu M, Sima AV, Stancu CS. Toma L, et al. Biomolecules. 2020 Apr 21;10(4):641. doi: 10.3390/biom10040641. Biomolecules. 2020. PMID: 32326376 Free PMC article. Review.
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