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A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant.
Agnihothram S, Yount BL Jr, Donaldson EF, Huynh J, Menachery VD, Gralinski LE, Graham RL, Becker MM, Tomar S, Scobey TD, Osswald HL, Whitmore A, Gopal R, Ghosh AK, Mesecar A, Zambon M, Heise M, Denison MR, Baric RS. Agnihothram S, et al. Among authors: tomar s. mBio. 2014 Mar 25;5(2):e00047-14. doi: 10.1128/mBio.00047-14. mBio. 2014. PMID: 24667706 Free PMC article.
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding.
Turlington M, Chun A, Tomar S, Eggler A, Grum-Tokars V, Jacobs J, Daniels JS, Dawson E, Saldanha A, Chase P, Baez-Santos YM, Lindsley CW, Hodder P, Mesecar AD, Stauffer SR. Turlington M, et al. Among authors: tomar s. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6172-7. doi: 10.1016/j.bmcl.2013.08.112. Epub 2013 Sep 7. Bioorg Med Chem Lett. 2013. PMID: 24080461 Free PMC article.
Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease.
Jacobs J, Grum-Tokars V, Zhou Y, Turlington M, Saldanha SA, Chase P, Eggler A, Dawson ES, Baez-Santos YM, Tomar S, Mielech AM, Baker SC, Lindsley CW, Hodder P, Mesecar A, Stauffer SR. Jacobs J, et al. Among authors: tomar s. J Med Chem. 2013 Jan 24;56(2):534-46. doi: 10.1021/jm301580n. Epub 2013 Jan 3. J Med Chem. 2013. PMID: 23231439 Free PMC article.
Crystallization and preliminary X-ray diffraction analysis of the complex of Kunitz-type tamarind trypsin inhibitor and porcine pancreatic trypsin.
Tomar S, Patil DN, Datta M, Tapas S, Preeti, Chaudhary A, Sharma AK, Tomar S, Kumar P. Tomar S, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Nov 1;65(Pt 11):1179-81. doi: 10.1107/S1744309109041694. Epub 2009 Oct 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19923745 Free PMC article.
480 results