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Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal R, Wagner JUG, Braeuning C, Fischer C, Patrick R, Tombor L, Muhly-Reinholz M, John D, Kliem M, Conrad T, Guimarães-Camboa N, Harvey R, Dimmeler S, Sauer S. Vidal R, et al. Among authors: tombor l. JCI Insight. 2019 Nov 14;4(22):e131092. doi: 10.1172/jci.insight.131092. JCI Insight. 2019. PMID: 31723062 Free PMC article.
Dissection of heterocellular cross-talk in vascularized cardiac tissue mimetics.
Wagner JUG, Pham MD, Nicin L, Hammer M, Bottermann K, Yuan T, Sharma R, John D, Muhly-Reinholz M, Tombor L, Hardt M, Madl J, Dimmeler S, Krishnan J. Wagner JUG, et al. Among authors: tombor l. J Mol Cell Cardiol. 2020 Jan;138:269-282. doi: 10.1016/j.yjmcc.2019.12.005. Epub 2019 Dec 19. J Mol Cell Cardiol. 2020. PMID: 31866374 Free article.
The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition.
Glaser SF, Heumüller AW, Tombor L, Hofmann P, Muhly-Reinholz M, Fischer A, Günther S, Kokot KE, Hassel D, Kumar S, Jo H, Boon RA, Abplanalp W, John D, Boeckel JN, Dimmeler S. Glaser SF, et al. Among authors: tombor l. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4180-4187. doi: 10.1073/pnas.1913481117. Epub 2020 Feb 7. Proc Natl Acad Sci U S A. 2020. PMID: 32034099 Free PMC article.
Cell type-specific expression of the putative SARS-CoV-2 receptor ACE2 in human hearts.
Nicin L, Abplanalp WT, Mellentin H, Kattih B, Tombor L, John D, Schmitto JD, Heineke J, Emrich F, Arsalan M, Holubec T, Walther T, Zeiher AM, Dimmeler S. Nicin L, et al. Among authors: tombor l. Eur Heart J. 2020 May 14;41(19):1804-1806. doi: 10.1093/eurheartj/ehaa311. Eur Heart J. 2020. PMID: 32293672 Free PMC article. No abstract available.
Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function.
Bibli SI, Hu J, Looso M, Weigert A, Ratiu C, Wittig J, Drekolia MK, Tombor L, Randriamboavonjy V, Leisegang MS, Goymann P, Delgado Lagos F, Fisslthaler B, Zukunft S, Kyselova A, Justo AFO, Heidler J, Tsilimigras D, Brandes RP, Dimmeler S, Papapetropoulos A, Knapp S, Offermanns S, Wittig I, Nishimura SL, Sigala F, Fleming I. Bibli SI, et al. Among authors: tombor l. Circulation. 2021 Mar 2;143(9):935-948. doi: 10.1161/CIRCULATIONAHA.120.051877. Epub 2020 Dec 14. Circulation. 2021. PMID: 33307764
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.
Tombor LS, John D, Glaser SF, Luxán G, Forte E, Furtado M, Rosenthal N, Baumgarten N, Schulz MH, Wittig J, Rogg EM, Manavski Y, Fischer A, Muhly-Reinholz M, Klee K, Looso M, Selignow C, Acker T, Bibli SI, Fleming I, Patrick R, Harvey RP, Abplanalp WT, Dimmeler S. Tombor LS, et al. Nat Commun. 2021 Jan 29;12(1):681. doi: 10.1038/s41467-021-20905-1. Nat Commun. 2021. PMID: 33514719 Free PMC article.
Single Nuclei Sequencing Reveals Novel Insights Into the Regulation of Cellular Signatures in Children With Dilated Cardiomyopathy.
Nicin L, Abplanalp WT, Schänzer A, Sprengel A, John D, Mellentin H, Tombor L, Keuper M, Ullrich E, Klingel K, Dettmeyer RB, Hoffmann J, Akintuerk H, Jux C, Schranz D, Zeiher AM, Rupp S, Dimmeler S. Nicin L, et al. Among authors: tombor l. Circulation. 2021 Apr 27;143(17):1704-1719. doi: 10.1161/CIRCULATIONAHA.120.051391. Epub 2021 Feb 23. Circulation. 2021. PMID: 33618539
The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice.
Buchmann GK, Schürmann C, Spaeth M, Abplanalp W, Tombor L, John D, Warwick T, Rezende F, Weigert A, Shah AM, Hansmann ML, Weissmann N, Dimmeler S, Schröder K, Brandes RP. Buchmann GK, et al. Among authors: tombor l. Redox Biol. 2021 Sep;45:102050. doi: 10.1016/j.redox.2021.102050. Epub 2021 Jun 18. Redox Biol. 2021. PMID: 34218201 Free PMC article.
39 results