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717 results
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Colorectal cancer and genetic alterations in the Wnt pathway.
Segditsas S, Tomlinson I. Segditsas S, et al. Among authors: tomlinson i. Oncogene. 2006 Dec 4;25(57):7531-7. doi: 10.1038/sj.onc.1210059. Oncogene. 2006. PMID: 17143297 Review.
Population genetics of tumours.
Bodmer WF, Tomlinson I. Bodmer WF, et al. Among authors: tomlinson i. Ciba Found Symp. 1996;197:181-9; discussion 189-93. doi: 10.1002/9780470514887.ch10. Ciba Found Symp. 1996. PMID: 8827374 Review.
Molecular genetics of colon cancer.
Tomlinson I, Ilyas M, Novelli M. Tomlinson I, et al. Cancer Metastasis Rev. 1997 Jun;16(1-2):67-79. doi: 10.1023/a:1005744323215. Cancer Metastasis Rev. 1997. PMID: 9156280 Review.
Reciprocity between membranous and nuclear expression of beta-catenin in colorectal tumours.
Hao X, Tomlinson I, Ilyas M, Palazzo JP, Talbot IC. Hao X, et al. Among authors: tomlinson i. Virchows Arch. 1997 Sep;431(3):167-72. doi: 10.1007/s004280050084. Virchows Arch. 1997. PMID: 9334837
Selection, the mutation rate and cancer: ensuring that the tail does not wag the dog.
Tomlinson I, Bodmer W. Tomlinson I, et al. Nat Med. 1999 Jan;5(1):11-2. doi: 10.1038/4687. Nat Med. 1999. PMID: 9883827 Review. No abstract available.
Inherited susceptibility to colorectal adenomas and carcinomas: evidence for a new predisposition gene on 15q14-q22.
Tomlinson I, Rahman N, Frayling I, Mangion J, Barfoot R, Hamoudi R, Seal S, Northover J, Thomas HJ, Neale K, Hodgson S, Talbot I, Houlston R, Stratton MR. Tomlinson I, et al. Gastroenterology. 1999 Apr;116(4):789-95. doi: 10.1016/s0016-5085(99)70061-2. Gastroenterology. 1999. PMID: 10092300
Somatic mutations in the Peutz-Jeghers (LKB1/STKII) gene in sporadic malignant melanomas.
Rowan A, Bataille V, MacKie R, Healy E, Bicknell D, Bodmer W, Tomlinson I. Rowan A, et al. Among authors: tomlinson i. J Invest Dermatol. 1999 Apr;112(4):509-11. doi: 10.1046/j.1523-1747.1999.00551.x. J Invest Dermatol. 1999. PMID: 10201537
Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome.
Bevan S, Woodford-Richens K, Rozen P, Eng C, Young J, Dunlop M, Neale K, Phillips R, Markie D, Rodriguez-Bigas M, Leggett B, Sheridan E, Hodgson S, Iwama T, Eccles D, Bodmer W, Houlston R, Tomlinson I. Bevan S, et al. Among authors: tomlinson i. Gut. 1999 Sep;45(3):406-8. doi: 10.1136/gut.45.3.406. Gut. 1999. PMID: 10446110 Free PMC article.
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.
Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, Frayling I, Efstathiou J, Pack K, Payne S, Roylance R, Gorman P, Sheer D, Neale K, Phillips R, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Among authors: tomlinson i. Nat Med. 1999 Sep;5(9):1071-5. doi: 10.1038/12511. Nat Med. 1999. PMID: 10470088
Different pathways of colorectal carcinogenesis and their clinical pictures.
Tomlinson I. Tomlinson I. Ann N Y Acad Sci. 2000 Jun;910:10-8; discussion 18-20. doi: 10.1111/j.1749-6632.2000.tb06697.x. Ann N Y Acad Sci. 2000. PMID: 10911902 Review.
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