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Genetic pathways in colorectal cancer.
Ilyas M, Tomlinson IP. Ilyas M, et al. Histopathology. 1996 May;28(5):389-99. doi: 10.1046/j.1365-2559.1996.339381.x. Histopathology. 1996. PMID: 8735714 Review.
APC mutations are sufficient for the growth of early colorectal adenomas.
Lamlum H, Papadopoulou A, Ilyas M, Rowan A, Gillet C, Hanby A, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2225-8. doi: 10.1073/pnas.040564697. Proc Natl Acad Sci U S A. 2000. PMID: 10681434 Free PMC article.
A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer.
Tomlinson I, Ilyas M, Johnson V, Davies A, Clark G, Talbot I, Bodmer W. Tomlinson I, et al. J Pathol. 1998 Feb;184(2):148-52. doi: 10.1002/(SICI)1096-9896(199802)184:2<148::AID-PATH986>3.0.CO;2-M. J Pathol. 1998. PMID: 9602705
Mutations, evolutionary theory and cancer.
Tomlinson I. Tomlinson I. Trends Ecol Evol. 1993 Mar;8(3):107-10. doi: 10.1016/0169-5347(93)90062-T. Trends Ecol Evol. 1993. PMID: 21236121
Variability in the severity of colonic disease in familial adenomatous polyposis results from differences in tumour initiation rather than progression and depends relatively little on patient age.
Crabtree MD, Tomlinson IP, Talbot IC, Phillips RK. Crabtree MD, et al. Gut. 2001 Oct;49(4):540-3. doi: 10.1136/gut.49.4.540. Gut. 2001. PMID: 11559652 Free PMC article.
Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers.
Woodford-Richens KL, Rowan AJ, Poulsom R, Bevan S, Salovaara R, Aaltonen LA, Houlston RS, Wright NA, Tomlinson IP. Woodford-Richens KL, et al. Am J Pathol. 2001 Oct;159(4):1293-300. doi: 10.1016/S0002-9440(10)62516-3. Am J Pathol. 2001. PMID: 11583957 Free PMC article.
Polymorphisms and colorectal tumor risk.
Houlston RS, Tomlinson IP. Houlston RS, et al. Gastroenterology. 2001 Aug;121(2):282-301. doi: 10.1053/gast.2001.26265. Gastroenterology. 2001. PMID: 11487538
Optimising methods for determining RER status in colorectal cancers.
Stone JG, Tomlinson IP, Houlston RS. Stone JG, et al. Cancer Lett. 2000 Feb 28;149(1-2):15-20. doi: 10.1016/s0304-3835(99)00324-9. Cancer Lett. 2000. PMID: 10737703
Detecting low penetrance genes in cancer: the way ahead.
Houlston RS, Tomlinson IP. Houlston RS, et al. J Med Genet. 2000 Mar;37(3):161-7. doi: 10.1136/jmg.37.3.161. J Med Genet. 2000. PMID: 10699050 Free PMC article. Review.
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