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Fyn regulates the duration of TCR engagement needed for commitment to effector function.
Filby A, Seddon B, Kleczkowska J, Salmond R, Tomlinson P, Smida M, Lindquist JA, Schraven B, Zamoyska R. Filby A, et al. J Immunol. 2007 Oct 1;179(7):4635-44. doi: 10.4049/jimmunol.179.7.4635. J Immunol. 2007. PMID: 17878361
Early growth response (Egr)-1 gene induction in the thymus in response to TCR ligation during early steps in positive selection is not required for CD8 lineage commitment.
Basson MA, Wilson TJ, Legname GA, Sarner N, Tomlinson PD, Tybulewicz VL, Zamoyska R. Basson MA, et al. J Immunol. 2000 Sep 1;165(5):2444-50. doi: 10.4049/jimmunol.165.5.2444. J Immunol. 2000. PMID: 10946269
Tolerance induction by elimination of subsets of self-reactive thymocytes.
Sponaas AM, Tomlinson PD, Schulz R, Antoniou J, Ize-Iyamu P, Schmitt-Verhulst AM, Mellor AL. Sponaas AM, et al. Int Immunol. 1994 Oct;6(10):1593-604. doi: 10.1093/intimm/6.10.1593. Int Immunol. 1994. PMID: 7826949
Expression and function of Qa-2 major histocompatibility complex class I molecules in transgenic mice.
Mellor AL, Tomlinson PD, Antoniou J, Chandler P, Robinson P, Felstein M, Sloan J, Edwards A, O'Reilly L, Cooke A, et al. Mellor AL, et al. Int Immunol. 1991 May;3(5):493-502. doi: 10.1093/intimm/3.5.493. Int Immunol. 1991. PMID: 1911536
Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters.
Sponaas AM, Tomlinson PD, Antoniou J, Auphan N, Langlet C, Malissen B, Schmitt-Verhulst AM, Mellor AL. Sponaas AM, et al. Int Immunol. 1994 Feb;6(2):277-87. doi: 10.1093/intimm/6.2.277. Int Immunol. 1994. PMID: 7512374
HLA-G functions as a restriction element and a transplantation antigen in mice.
Horuzsko A, Antoniou J, Tomlinson P, Portik-Dobos V, Mellor AL. Horuzsko A, et al. Int Immunol. 1997 May;9(5):645-53. doi: 10.1093/intimm/9.5.645. Int Immunol. 1997. PMID: 9184910
Unprimed T cells are inefficiently stimulated by glycosylphosphatidylinositol-linked H-2Kb because of its lipid anchor rather than defects in CD8 binding.
Zamoyska R, Ong T, Kwan-Lim G, Tomlinson P, Robinson PJ. Zamoyska R, et al. Int Immunol. 1996 Apr;8(4):551-7. doi: 10.1093/intimm/8.4.551. Int Immunol. 1996. PMID: 8671642
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