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2002 1
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87 results

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Page 1
Activation of STING requires palmitoylation at the Golgi.
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, Barber GN, Arai H, Taguchi T. Mukai K, et al. Among authors: taguchi t. Nat Commun. 2016 Jun 21;7:11932. doi: 10.1038/ncomms11932. Nat Commun. 2016. PMID: 27324217 Free PMC article.
STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes.
Kuchitsu Y, Mukai K, Uematsu R, Takaada Y, Shinojima A, Shindo R, Shoji T, Hamano S, Ogawa E, Sato R, Miyake K, Kato A, Kawaguchi Y, Nishitani-Isa M, Izawa K, Nishikomori R, Yasumi T, Suzuki T, Dohmae N, Uemura T, Barber GN, Arai H, Waguri S, Taguchi T. Kuchitsu Y, et al. Among authors: taguchi t. Nat Cell Biol. 2023 Mar;25(3):453-466. doi: 10.1038/s41556-023-01098-9. Epub 2023 Mar 13. Nat Cell Biol. 2023. PMID: 36918692 Free PMC article.
Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism.
Ogawa A, Watanabe S, Ozerova I, Tsai AY, Kuchitsu Y, Chong HB, Kawakami T, Fuse J, Han W, Kudo R, Naito T, Sato K, Nakazawa T, Saheki Y, Hirayama A, Stadler PF, Arisawa M, Araki K, Bar-Peled L, Taguchi T, Sawa S, Inaba K, Wei FY. Ogawa A, et al. Among authors: taguchi t. Cell. 2025 Oct 30;188(22):6151-6169.e24. doi: 10.1016/j.cell.2025.07.041. Epub 2025 Aug 20. Cell. 2025. PMID: 40840445 Free article.
Homeostatic regulation of STING by retrograde membrane traffic to the ER.
Mukai K, Ogawa E, Uematsu R, Kuchitsu Y, Kiku F, Uemura T, Waguri S, Suzuki T, Dohmae N, Arai H, Shum AK, Taguchi T. Mukai K, et al. Among authors: taguchi t. Nat Commun. 2021 Jan 4;12(1):61. doi: 10.1038/s41467-020-20234-9. Nat Commun. 2021. PMID: 33397928 Free PMC article.
Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol.
Kemmoku H, Takahashi K, Mukai K, Mori T, Hirosawa KM, Kiku F, Uchida Y, Kuchitsu Y, Nishioka Y, Sawa M, Kishimoto T, Tanaka K, Yokota Y, Arai H, Suzuki KGN, Taguchi T. Kemmoku H, et al. Among authors: taguchi t. Nat Commun. 2024 Jan 11;15(1):220. doi: 10.1038/s41467-023-44317-5. Nat Commun. 2024. PMID: 38212328 Free PMC article.
Class B1 GPCR activation by an intracellular agonist.
Kobayashi K, Kawakami K, Kusakizako T, Tomita A, Nishimura M, Sawada K, Okamoto HH, Hiratsuka S, Nakamura G, Kuwabara R, Noda H, Muramatsu H, Shimizu M, Taguchi T, Inoue A, Murata T, Nureki O. Kobayashi K, et al. Among authors: taguchi t. Nature. 2023 Jun;618(7967):1085-1093. doi: 10.1038/s41586-023-06169-3. Epub 2023 Jun 7. Nature. 2023. PMID: 37286611 Free PMC article.
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress.
Kobayashi T, Nguyen-Tien D, Sorimachi Y, Sugiura Y, Suzuki T, Karyu H, Shimabukuro-Demoto S, Uemura T, Okamura T, Taguchi T, Ueki K, Kato N, Goda N, Dohmae N, Takubo K, Suematsu M, Toyama-Sorimachi N. Kobayashi T, et al. Among authors: taguchi t. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2100295118. doi: 10.1073/pnas.2100295118. Proc Natl Acad Sci U S A. 2021. PMID: 34385317 Free PMC article.
Mentoring the next generation of cell biologists.
Applewhite DA, Bhalla N, Cabezas-Wallscheid N, Erez N, Li M, Polo JM, Taguchi T, Thiam AR, Wang X. Applewhite DA, et al. Among authors: taguchi t. Nat Cell Biol. 2024 Jan;26(1):15-18. doi: 10.1038/s41556-023-01278-7. Nat Cell Biol. 2024. PMID: 38228826 No abstract available.
The common HAQ STING allele prevents clinical penetrance of COPA syndrome.
Simchoni N, Koide S, Likhite M, Kuchitsu Y, Kadirvel S, Law CS, Elicker BM, Kurra S, Wong MM, Yuan B, Grossi A, Laxer RM, Volpi S, Dissanayake D, Taguchi T, Beck DB, Vogel TP, Shum AK. Simchoni N, et al. Among authors: taguchi t. J Exp Med. 2025 Apr 7;222(4):e20242179. doi: 10.1084/jem.20242179. Epub 2025 Feb 27. J Exp Med. 2025. PMID: 40014299 Free PMC article.
87 results