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Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery.
Tong L. Tong L. Cell Mol Life Sci. 2005 Aug;62(16):1784-803. doi: 10.1007/s00018-005-5121-4. Cell Mol Life Sci. 2005. PMID: 15968460 Review.
Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme: a new class of oxidative decarboxylases.
Xu Y, Bhargava G, Wu H, Loeber G, Tong L. Xu Y, et al. Among authors: tong l. Structure. 1999 Aug 15;7(8):R877-89. Structure. 1999. PMID: 10477256
Structure of a closed form of human malic enzyme and implications for catalytic mechanism.
Yang Z, Floyd DL, Loeber G, Tong L. Yang Z, et al. Among authors: tong l. Nat Struct Biol. 2000 Mar;7(3):251-7. doi: 10.1038/73378. Nat Struct Biol. 2000. PMID: 10700286
Potent and competitive inhibition of malic enzymes by lanthanide ions.
Yang Z, Batra R, Floyd DL, Hung HC, Chang GG, Tong L. Yang Z, et al. Among authors: tong l. Biochem Biophys Res Commun. 2000 Aug 2;274(2):440-4. doi: 10.1006/bbrc.2000.3163. Biochem Biophys Res Commun. 2000. PMID: 10913357
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Xu Y, Tao X, Shen B, Horng T, Medzhitov R, Manley JL, Tong L. Xu Y, et al. Among authors: tong l. Nature. 2000 Nov 2;408(6808):111-5. doi: 10.1038/35040600. Nature. 2000. PMID: 11081518
Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
Khayat R, Batra R, Massariol MJ, Lagacé L, Tong L. Khayat R, et al. Among authors: tong l. Biochemistry. 2001 May 29;40(21):6344-51. doi: 10.1021/bi010158b. Biochemistry. 2001. PMID: 11371196
Solution-state NMR investigations of triosephosphate isomerase active site loop motion: ligand release in relation to active site loop dynamics.
Rozovsky S, Jogl G, Tong L, McDermott AE. Rozovsky S, et al. Among authors: tong l. J Mol Biol. 2001 Jun 29;310(1):271-80. doi: 10.1006/jmbi.2001.4673. J Mol Biol. 2001. PMID: 11419952
Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease.
Batra R, Khayat R, Tong L. Batra R, et al. Among authors: tong l. Nat Struct Biol. 2001 Sep;8(9):810-7. doi: 10.1038/nsb0901-810. Nat Struct Biol. 2001. PMID: 11524687
Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme.
Yang Z, Zhang H, Hung HC, Kuo CC, Tsai LC, Yuan HS, Chou WY, Chang GG, Tong L. Yang Z, et al. Among authors: tong l. Protein Sci. 2002 Feb;11(2):332-41. doi: 10.1110/ps.38002. Protein Sci. 2002. PMID: 11790843 Free PMC article.
Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate.
Yang Z, Lanks CW, Tong L. Yang Z, et al. Among authors: tong l. Structure. 2002 Jul;10(7):951-60. doi: 10.1016/s0969-2126(02)00788-8. Structure. 2002. PMID: 12121650
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