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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 1
1967 1
1969 1
1970 3
1971 5
1972 4
1973 1
1975 1
1976 2
1977 5
1978 1
1979 4
1980 2
1981 10
1982 4
1983 3
1984 9
1985 11
1986 12
1987 15
1988 10
1989 6
1990 8
1991 4
1992 13
1993 10
1994 13
1995 10
1996 11
1997 12
1998 16
1999 19
2000 21
2001 10
2002 17
2003 22
2004 32
2005 43
2006 60
2007 65
2008 70
2009 85
2010 99
2011 87
2012 90
2013 111
2014 84
2015 113
2016 140
2017 136
2018 149
2019 143
2020 27
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1,639 results
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Page 1
Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis
Lin Z, et al. Cell Res 2017. Among authors: Tong MH. PMID 28914256 Free PMC article.
Here we report that N(6)-methyladenosine (m(6)A), an epitranscriptomic mark regulating gene expression, plays essential roles during spermatogenesis. ...Germ cell-specific inactivation of the m(6)A RNA methyltransferase Mettl3 or Mettl14 with Vasa-Cre causes loss of m(6)A and depletion of SSCs. m(6)A depletion dysregulates translation of transcripts that are required for SSC proliferation/differentiation. ...
Here we report that N(6)-methyladenosine (m(6)A), an epitranscriptomic mark regulating gene expression, plays essential roles during …
m(6)A mRNA modification regulates mammalian spermatogenesis.
Lin Z and Tong MH. Biochim Biophys Acta Gene Regul Mech 2019 - Review. PMID 30391644
Emerging evidence has shown that N(6)-methyladenosine (m(6)A), an epitranscriptomic regulator of gene expression, can influence pre-mRNA splicing, mRNA export, turnover, and translation, which are controlled in the male germline to ensure coordinated gene expression. In this review, we summarize the typical features of m(6)A RNA modification on mRNA during male germline development, and highlight the function of writers, erasers, and readers of m(6)A during mouse spermatogenesis....
Emerging evidence has shown that N(6)-methyladenosine (m(6)A), an epitranscriptomic regulator of gene expression, can influence pre-m …
1,639 results
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