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Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.
Benedetti S, Uno N, Hoshiya H, Ragazzi M, Ferrari G, Kazuki Y, Moyle LA, Tonlorenzi R, Lombardo A, Chaouch S, Mouly V, Moore M, Popplewell L, Kazuki K, Katoh M, Naldini L, Dickson G, Messina G, Oshimura M, Cossu G, Tedesco FS. Benedetti S, et al. Among authors: tonlorenzi r. EMBO Mol Med. 2018 Feb;10(2):254-275. doi: 10.15252/emmm.201607284. EMBO Mol Med. 2018. PMID: 29242210 Free PMC article.
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.
Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, Antonini S, Tagliafico E, Artusi V, Longa E, Tonlorenzi R, Ragazzi M, Calderazzi G, Hoshiya H, Cappellari O, Mora M, Schoser B, Schneiderat P, Oshimura M, Bottinelli R, Sampaolesi M, Torrente Y, Broccoli V, Cossu G. Tedesco FS, et al. Among authors: tonlorenzi r. Sci Transl Med. 2012 Jun 27;4(140):140ra89. doi: 10.1126/scitranslmed.3003541. Sci Transl Med. 2012. PMID: 22745439
Inflammation converts human mesoangioblasts into targets of alloreactive immune responses: implications for allogeneic cell therapy of DMD.
Noviello M, Tedesco FS, Bondanza A, Tonlorenzi R, Rosaria Carbone M, Gerli MFM, Marktel S, Napolitano S, Cicalese MP, Ciceri F, Peretti G, Cossu G, Bonini C. Noviello M, et al. Among authors: tonlorenzi r. Mol Ther. 2014 Jul;22(7):1342-1352. doi: 10.1038/mt.2014.62. Epub 2014 Apr 16. Mol Ther. 2014. PMID: 24736278 Free PMC article.
Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells.
Dellavalle A, Sampaolesi M, Tonlorenzi R, Tagliafico E, Sacchetti B, Perani L, Innocenzi A, Galvez BG, Messina G, Morosetti R, Li S, Belicchi M, Peretti G, Chamberlain JS, Wright WE, Torrente Y, Ferrari S, Bianco P, Cossu G. Dellavalle A, et al. Among authors: tonlorenzi r. Nat Cell Biol. 2007 Mar;9(3):255-67. doi: 10.1038/ncb1542. Epub 2007 Feb 11. Nat Cell Biol. 2007. PMID: 17293855
Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs.
Sampaolesi M, Blot S, D'Antona G, Granger N, Tonlorenzi R, Innocenzi A, Mognol P, Thibaud JL, Galvez BG, Barthélémy I, Perani L, Mantero S, Guttinger M, Pansarasa O, Rinaldi C, Cusella De Angelis MG, Torrente Y, Bordignon C, Bottinelli R, Cossu G. Sampaolesi M, et al. Among authors: tonlorenzi r. Nature. 2006 Nov 30;444(7119):574-9. doi: 10.1038/nature05282. Epub 2006 Nov 15. Nature. 2006. PMID: 17108972
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