Toogood PL - Search Results

1

Inhibition of protein synthesis by didemnin B: how EF-1alpha mediates inhibition of translocation.

Ahuja D, Vera MD, SirDeshpande BV, Morimoto H, Williams PG, Joullié MM, Toogood PL. Ahuja D, et al. Among authors: toogood pl. Biochemistry. 2000 Apr 18;39(15):4339-46. doi: 10.1021/bi992202h. Biochemistry. 2000. PMID: 10757982

2

Mechanism of protein synthesis inhibition by didemnin B in vitro.

SirDeshpande BV, Toogood PL. SirDeshpande BV, et al. Among authors: toogood pl. Biochemistry. 1995 Jul 18;34(28):9177-84. doi: 10.1021/bi00028a030. Biochemistry. 1995. PMID: 7619818

3

Inhibition of protein synthesis by didemnin B is not sufficient to induce apoptosis in human mammary carcinoma (MCF7) cells.

Beidler DR, Ahuja D, Wicha MS, Toogood PL. Beidler DR, et al. Among authors: toogood pl. Biochem Pharmacol. 1999 Sep 15;58(6):1067-74. doi: 10.1016/s0006-2952(99)00193-8. Biochem Pharmacol. 1999. PMID: 10509759

4

Inhibition of protein synthesis by didemnins: cell potency and SAR.

Ahuja D, Geiger A, Ramanjulu JM, Vera MD, SirDeshpande B, Pfizenmayer A, Abazeed M, Krosky DJ, Beidler D, Joullié MM, Toogood PL. Ahuja D, et al. Among authors: toogood pl. J Med Chem. 2000 Nov 2;43(22):4212-8. doi: 10.1021/jm000168v. J Med Chem. 2000. PMID: 11063617

5

Synthesis and biological evaluation of didemnin photoaffinity analogues.

Vera MD, Pfizenmayer AJ, Ding X, Ahuja D, Toogood PL, Joullié MM. Vera MD, et al. Among authors: toogood pl. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1871-4. doi: 10.1016/s0960-894x(01)00339-0. Bioorg Med Chem Lett. 2001. PMID: 11459650

6

Inhibition of protein-protein association by small molecules: approaches and progress.

Toogood PL. Toogood PL. J Med Chem. 2002 Apr 11;45(8):1543-58. doi: 10.1021/jm010468s. J Med Chem. 2002. PMID: 11931608 Review. No abstract available.

7

Cyclin-dependent kinase inhibitors for treating cancer.

Toogood PL. Toogood PL. Med Res Rev. 2001 Nov;21(6):487-98. doi: 10.1002/med.1021. Med Res Rev. 2001. PMID: 11607930 Review.

8

Total Synthesis of Motuporin and 5-[L-Ala]-Motuporin.

Samy R, Kim HY, Brady M, Toogood PL. Samy R, et al. Among authors: toogood pl. J Org Chem. 1999 Apr 16;64(8):2711-2728. doi: 10.1021/jo982145i. J Org Chem. 1999. PMID: 11674341

9

Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases.

Barvian M, Boschelli DH, Cossrow J, Dobrusin E, Fattaey A, Fritsch A, Fry D, Harvey P, Keller P, Garrett M, La F, Leopold W, McNamara D, Quin M, Trumpp-Kallmeyer S, Toogood P, Wu Z, Zhang E. Barvian M, et al. J Med Chem. 2000 Nov 30;43(24):4606-16. doi: 10.1021/jm000271k. J Med Chem. 2000. PMID: 11101352

10

The kinome is not enough.

Toogood PL. Toogood PL. Chem Biol. 2005 Oct;12(10):1057-8. doi: 10.1016/j.chembiol.2005.09.011. Chem Biol. 2005. PMID: 16242646 Review.

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