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Linagliptin monotherapy in type 2 diabetes patients for whom metformin is inappropriate: an 18-week randomized, double-blind, placebo-controlled phase III trial with a 34-week active-controlled extension.
Diabetes Obes Metab. 2012 Dec;14(12):1145-54. doi: 10.1111/dom.12011. Epub 2012 Oct 1.
Diabetes Obes Metab. 2012.
PMID: 22974280
Clinical Trial.
Linagliptin and pioglitazone combination therapy versus monotherapy with linagliptin or pioglitazone: A randomised, double-blind, parallel-group, multinational clinical trial.
Nauck MA, di Domenico M, Patel S, Kobe M, Toorawa R, Woerle HJ.
Nauck MA, et al. Among authors: toorawa r.
Diab Vasc Dis Res. 2016 Jul;13(4):286-98. doi: 10.1177/1479164116639229. Epub 2016 May 5.
Diab Vasc Dis Res. 2016.
PMID: 27190087
Free article.
Clinical Trial.
Item in Clipboard
Empagliflozin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Linagliptin and Metformin: A 24-Week Randomized, Double-Blind, Parallel-Group Trial.
Søfteland E, Meier JJ, Vangen B, Toorawa R, Maldonado-Lutomirsky M, Broedl UC.
Søfteland E, et al. Among authors: toorawa r.
Diabetes Care. 2017 Feb;40(2):201-209. doi: 10.2337/dc16-1347. Epub 2016 Dec 2.
Diabetes Care. 2017.
PMID: 27913576
Clinical Trial.
Item in Clipboard
Efficacy and safety of linagliptin 2.5 mg twice daily versus 5 mg once daily in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, placebo-controlled trial.
Ross SA, Rafeiro E, Meinicke T, Toorawa R, Weber-Born S, Woerle HJ.
Ross SA, et al. Among authors: toorawa r.
Curr Med Res Opin. 2012 Sep;28(9):1465-74. doi: 10.1185/03007995.2012.714360. Epub 2012 Aug 13.
Curr Med Res Opin. 2012.
PMID: 22816729
Clinical Trial.
Item in Clipboard
Randomised, double-blind, placebo-controlled crossover study to investigate different dosing regimens of olodaterol delivered via Respimat® in patients with moderate to severe persistent asthma.
Beeh KM, LaForce C, Gahlemann M, Wenz A, Toorawa R, Fležar M.
Beeh KM, et al. Among authors: toorawa r.
Respir Res. 2015 Jul 16;16(1):87. doi: 10.1186/s12931-015-0243-1.
Respir Res. 2015.
PMID: 26177937
Free PMC article.
Clinical Trial.
Item in Clipboard
Dose-finding evaluation of once-daily treatment with olodaterol, a novel long-acting β2-agonist, in patients with asthma: results of a parallel-group study and a crossover study.
O'Byrne PM, D'Urzo T, Beck E, Fležar M, Gahlemann M, Hart L, Blahova Z, Toorawa R, Beeh KM.
O'Byrne PM, et al. Among authors: toorawa r.
Respir Res. 2015 Aug 18;16(1):97. doi: 10.1186/s12931-015-0249-8.
Respir Res. 2015.
PMID: 26283085
Free PMC article.
Clinical Trial.
Item in Clipboard
Use of simulation to compare the performance of minimization with stratified blocked randomization.
Toorawa R, Adena M, Donovan M, Jones S, Conlon J.
Toorawa R, et al.
Pharm Stat. 2009 Oct-Dec;8(4):264-78. doi: 10.1002/pst.346.
Pharm Stat. 2009.
PMID: 18756580
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