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The development of gene therapy for the treatment of cancer.
Rosenberg SA, Anderson WF, Blaese M, Hwu P, Yannelli JR, Yang JC, Topalian SL, Schwartzentruber DJ, Weber JS, Ettinghausen SE, et al. Rosenberg SA, et al. Among authors: topalian sl. Ann Surg. 1993 Oct;218(4):455-63; discussion 463-4. doi: 10.1097/00000658-199310000-00006. Ann Surg. 1993. PMID: 8215637 Free PMC article.
The use of polyethylene glycol-modified interleukin-2 (PEG-IL-2) in the treatment of patients with metastatic renal cell carcinoma and melanoma. A phase I study and a randomized prospective study comparing IL-2 alone versus IL-2 combined with PEG-IL-2.
Yang JC, Topalian SL, Schwartzentruber DJ, Parkinson DR, Marincola FM, Weber JS, Seipp CA, White DE, Rosenberg SA. Yang JC, et al. Among authors: topalian sl. Cancer. 1995 Aug 15;76(4):687-94. doi: 10.1002/1097-0142(19950815)76:4<687::aid-cncr2820760424>3.0.co;2-m. Cancer. 1995. PMID: 8625167 Clinical Trial.
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma.
Rosenberg SA, Yang JC, Schwartzentruber DJ, Hwu P, Marincola FM, Topalian SL, Restifo NP, Dudley ME, Schwarz SL, Spiess PJ, Wunderlich JR, Parkhurst MR, Kawakami Y, Seipp CA, Einhorn JH, White DE. Rosenberg SA, et al. Among authors: topalian sl. Nat Med. 1998 Mar;4(3):321-7. doi: 10.1038/nm0398-321. Nat Med. 1998. PMID: 9500606 Free PMC article. Clinical Trial.
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma.
Phan GQ, Yang JC, Sherry RM, Hwu P, Topalian SL, Schwartzentruber DJ, Restifo NP, Haworth LR, Seipp CA, Freezer LJ, Morton KE, Mavroukakis SA, Duray PH, Steinberg SM, Allison JP, Davis TA, Rosenberg SA. Phan GQ, et al. Among authors: topalian sl. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8372-7. doi: 10.1073/pnas.1533209100. Epub 2003 Jun 25. Proc Natl Acad Sci U S A. 2003. PMID: 12826605 Free PMC article. Clinical Trial.
171 results