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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1953 2
1955 1
1959 1
1961 1
1964 1
1966 1
1968 2
1970 2
1971 4
1973 5
1974 3
1975 3
1976 9
1977 5
1978 4
1979 6
1980 11
1981 11
1982 13
1983 23
1984 16
1985 17
1986 19
1987 11
1988 22
1989 33
1990 21
1991 16
1992 22
1993 14
1994 19
1995 30
1996 35
1997 29
1998 24
1999 40
2000 44
2001 39
2002 37
2003 34
2004 41
2005 41
2006 51
2007 50
2008 66
2009 64
2010 57
2011 52
2012 61
2013 66
2014 72
2015 75
2016 89
2017 72
2018 76
2019 77
2020 86
2021 82
2022 69
2023 62
2024 59
2025 60
2026 7

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1,876 results

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Page 1
Topical urea in skincare: A review.
Celleno L. Celleno L. Dermatol Ther. 2018 Nov;31(6):e12690. doi: 10.1111/dth.12690. Epub 2018 Oct 30. Dermatol Ther. 2018. PMID: 30378232 Review.
Here, we summarize the available clinical evidence regarding the effects of urea in the maintenance of healthy skin and management of skin disorders. At lower doses (10%), urea-containing topical formulations act as a skin moisturizer, while at higher concentrations (>1 …
Here, we summarize the available clinical evidence regarding the effects of urea in the maintenance of healthy skin and management of skin d …
The Therapeutic Use of Antioxidants for Melasma.
Babbush KM, Babbush RA, Khachemoune A. Babbush KM, et al. J Drugs Dermatol. 2020 Aug 1;19(8):788-792. doi: 10.36849/JDD.2020.5079. J Drugs Dermatol. 2020. PMID: 32845595 Review.
Melasma is a chronic dermatologic condition with an incompletely understood pathogenesis and well-demonstrated impact on patient quality of life. ...There is promising evidence for the use of these antioxidants, as topical, oral, and intra-venous preparations …
Melasma is a chronic dermatologic condition with an incompletely understood pathogenesis and well-demonstrated impact on patient qual …
Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial.
Paller AS, Simpson EL, Siegfried EC, Cork MJ, Wollenberg A, Arkwright PD, Soong W, Gonzalez ME, Schneider LC, Sidbury R, Lockshin B, Meltzer S, Wang Z, Mannent LP, Amin N, Sun Y, Laws E, Akinlade B, Dillon M, Kosloski MP, Kamal MA, Dubost-Brama A, Patel N, Weinreich DM, Yancopoulos GD, O'Malley JT, Bansal A; participating investigators. Paller AS, et al. Lancet. 2022 Sep 17;400(10356):908-919. doi: 10.1016/S0140-6736(22)01539-2. Lancet. 2022. PMID: 36116481 Free article. Clinical Trial.
We aimed to evaluate efficacy and safety of dupilumab with concomitant low-potency topical corticosteroids in children aged 6 months to younger than 6 years with moderate-to-severe atopic dermatitis. ...Eligible patients were aged 6 months to younger than 6 years, with mod …
We aimed to evaluate efficacy and safety of dupilumab with concomitant low-potency topical corticosteroids in children aged 6 months …
Post-Inflammatory Hyperpigmentation: A Review of Treatment Strategies.
Shenoy A, Madan R. Shenoy A, et al. J Drugs Dermatol. 2020 Aug 1;19(8):763-768. doi: 10.36849/JDD.2020.4887. J Drugs Dermatol. 2020. PMID: 32845587 Review.
Post-inflammatory hyperpigmentation (PIH) is a reactive process resulting from increased melanin or abnormal distribution of melanin secondary to inflammatory skin conditions, dermatologic therapies, and external stimuli. Because PIH is a common condition that has a substa …
Post-inflammatory hyperpigmentation (PIH) is a reactive process resulting from increased melanin or abnormal distribution of melanin seconda …
The 500 Dalton rule for the skin penetration of chemical compounds and drugs.
Bos JD, Meinardi MM. Bos JD, et al. Exp Dermatol. 2000 Jun;9(3):165-9. doi: 10.1034/j.1600-0625.2000.009003165.x. Exp Dermatol. 2000. PMID: 10839713 Review.
They cannot penetrate and thus cannot act as allergens in man; 2) the most commonly used pharmacological agents applied in topical dermatotherapy are all under 500 Dalton; 3) all known topical drugs used in transdermal drug-delivery systems are under 500 Dalt …
They cannot penetrate and thus cannot act as allergens in man; 2) the most commonly used pharmacological agents applied in topical …
Efficacy and Safety of Lebrikizumab in Combination With Topical Corticosteroids in Adolescents and Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial (ADhere).
Simpson EL, Gooderham M, Wollenberg A, Weidinger S, Armstrong A, Soung J, Ferrucci S, Lima RG, Witte MM, Xu W, ElMaraghy H, Natalie CR, Pierce E, Blauvelt A; ADhere Investigators. Simpson EL, et al. JAMA Dermatol. 2023 Feb 1;159(2):182-191. doi: 10.1001/jamadermatol.2022.5534. JAMA Dermatol. 2023. PMID: 36630140 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate efficacy and safety of LEB combined with low- to mid-potency topical corticosteroids (TCS) in patients with moderate-to-severe AD. DESIGN, SETTING, AND PARTICIPANTS: The ADhere trial was a 16-week randomized, double-blinded, placebo (PBO)-controlled, …
OBJECTIVE: To evaluate efficacy and safety of LEB combined with low- to mid-potency topical corticosteroids (TCS) in patients with mo …
Topical preparations and their use in dermatology.
Wohlrab J. Wohlrab J. J Dtsch Dermatol Ges. 2016 Nov;14(11):1061-1070. doi: 10.1111/ddg.13151. J Dtsch Dermatol Ges. 2016. PMID: 27879084 Review.
Proper selection, prescription, and application of topical preparations, depending on the respective indication, are key to professional and responsible medical practice. ...Optimal use of topical preparations also requires basic knowledge in pharmacok …
Proper selection, prescription, and application of topical preparations, depending on the respective indication, are key to pr …
Strategies for using topical corticosteroids in children and adults with eczema.
Lax SJ, Harvey J, Axon E, Howells L, Santer M, Ridd MJ, Lawton S, Langan S, Roberts A, Ahmed A, Muller I, Ming LC, Panda S, Chernyshov P, Carter B, Williams HC, Thomas KS, Chalmers JR. Lax SJ, et al. Cochrane Database Syst Rev. 2022 Mar 11;3(3):CD013356. doi: 10.1002/14651858.CD013356.pub2. Cochrane Database Syst Rev. 2022. PMID: 35275399 Free PMC article.
Other comparisons Other comparisons included newer versus older preparations of topical corticosteroids (15 trials), cream versus ointment (7 trials), topical corticosteroids with wet wrap versus no wet wrap (6 trials), number of days per week applied (4 tria …
Other comparisons Other comparisons included newer versus older preparations of topical corticosteroids (15 trials), cream ver …
Safety of dermatologic medications in pregnancy and lactation: Part I. Pregnancy.
Murase JE, Heller MM, Butler DC. Murase JE, et al. J Am Acad Dermatol. 2014 Mar;70(3):401.e1-14; quiz 415. doi: 10.1016/j.jaad.2013.09.010. J Am Acad Dermatol. 2014. PMID: 24528911 Review.
Dermatologists are frequently faced with questions about the safety of commonly prescribed topical and systemic medications during pregnancy and lactation from women of childbearing age who are pregnant, considering pregnancy, or breastfeeding. ...Parts I and II of this co …
Dermatologists are frequently faced with questions about the safety of commonly prescribed topical and systemic medications during pr …
Topical use of dexpanthenol in skin disorders.
Ebner F, Heller A, Rippke F, Tausch I. Ebner F, et al. Am J Clin Dermatol. 2002;3(6):427-33. doi: 10.2165/00128071-200203060-00005. Am J Clin Dermatol. 2002. PMID: 12113650 Review.
Topical dexpanthenol acts like a moisturizer, improving stratum corneum hydration, reducing transepidermal water loss and maintaining skin softness and elasticity. ...Adjuvant skin care with dexpanthenol considerably improved the symptoms of skin irritation, such as drynes …
Topical dexpanthenol acts like a moisturizer, improving stratum corneum hydration, reducing transepidermal water loss and maintaining …
1,876 results