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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 3
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1966 4
1967 2
1968 10
1969 9
1970 5
1971 14
1972 12
1973 11
1974 18
1975 26
1976 12
1977 13
1978 12
1979 15
1980 10
1981 21
1982 15
1983 13
1984 8
1985 16
1986 16
1987 15
1988 15
1989 19
1990 16
1991 13
1992 15
1993 10
1994 18
1995 22
1996 13
1997 21
1998 14
1999 22
2000 26
2001 25
2002 25
2003 45
2004 27
2005 36
2006 49
2007 29
2008 34
2009 35
2010 42
2011 48
2012 42
2013 50
2014 57
2015 62
2016 58
2017 61
2018 66
2019 81
2020 67
2021 80
2022 106
2023 90
2024 98
2025 40

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1,694 results

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Page 1
Topical 5-fluorouracil in dermatologic disease.
Prince GT, Cameron MC, Fathi R, Alkousakis T. Prince GT, et al. Int J Dermatol. 2018 Oct;57(10):1259-1264. doi: 10.1111/ijd.14106. Epub 2018 Jun 25. Int J Dermatol. 2018. PMID: 30187924 Review.
BACKGROUND: 5-fluorouracil (5-FU) has proven to be an effective therapy in the treatment of a variety of dermatologic conditions. ...This review serves as a comprehensive summary of topical 5-FU use in dermatology....
BACKGROUND: 5-fluorouracil (5-FU) has proven to be an effective therapy in the treatment of a variety of dermatologic conditions. ... …
Clinical pharmacology of 5-fluorouracil.
Diasio RB, Harris BE. Diasio RB, et al. Clin Pharmacokinet. 1989 Apr;16(4):215-37. doi: 10.2165/00003088-198916040-00002. Clin Pharmacokinet. 1989. PMID: 2656050 Review.
The recent development of clinically useful pharmacodynamic assays provides an attractive alternative to plasma drug concentrations, since these assays allow the detection of active metabolites of 5-fluorouracil in biopsied tumour or normal tissue. 5-Fluorouracil is …
The recent development of clinically useful pharmacodynamic assays provides an attractive alternative to plasma drug concentrations, since t …
Topical Calcipotriol Plus 5-Fluorouracil in the Treatment of Actinic Keratosis, Bowen's Disease, and Squamous Cell Carcinoma: A Systematic Review.
Lapidus AH, Lee S, Liu ZF, Smithson S, Chew CY, Gin D. Lapidus AH, et al. J Cutan Med Surg. 2024 Jul-Aug;28(4):375-380. doi: 10.1177/12034754241256347. Epub 2024 May 23. J Cutan Med Surg. 2024. PMID: 38783539 Review.
BACKGROUND/OBJECTIVES: Actinic keratoses (AK) are premalignant skin lesions caused by chronic sun exposure, topically managed by 5-fluorouracil (5-FU), diclofenac 3% gel, and imiquimod. Despite their effectiveness, long treatment duration and severe adverse local sk …
BACKGROUND/OBJECTIVES: Actinic keratoses (AK) are premalignant skin lesions caused by chronic sun exposure, topically managed by 5- …
Topical chemotherapy with 5-fluorouracil. A review.
Goette DK. Goette DK. J Am Acad Dermatol. 1981 Jun;4(6):633-49. doi: 10.1016/s0190-9622(81)80196-x. J Am Acad Dermatol. 1981. PMID: 7016939 Review. No abstract available.
Keep Topical Fluorouracil far Away from Pets.
Shastay A. Shastay A. Home Healthc Now. 2022 Jul-Aug 01;40(4):226-227. doi: 10.1097/NHH.0000000000001087. Home Healthc Now. 2022. PMID: 35777946 No abstract available.
Basic pharmacology of topical imiquimod, 5-fluorouracil, and diclofenac for the dermatologic surgeon.
Desai T, Chen CL, Desai A, Kirby W. Desai T, et al. Dermatol Surg. 2012 Jan;38(1):97-103. doi: 10.1111/j.1524-4725.2011.02194.x. Epub 2011 Oct 14. Dermatol Surg. 2012. PMID: 22092926 Review.
As the incidence of NMSC continues to rise, topical therapies will be used with increasing frequency. Topical therapies may benefit high-risk surgical candidates as an alternative treatment modality and may improve overall cosmesis. The most commonly employed top …
As the incidence of NMSC continues to rise, topical therapies will be used with increasing frequency. Topical therapies may be …
Topical treatment of actinic keratosis with fluorouracil: is irritation associated with efficacy?
Jorizzo J. Jorizzo J. J Drugs Dermatol. 2004 Jan-Feb;3(1):21-6. J Drugs Dermatol. 2004. PMID: 14964743 Review.
Therapeutic options include destructive modalities (i.e., cryosurgery, curettage) or topical fluorouracil treatment. The efficacy of topical fluorouracil for the treatment of widespread AK lesions has been demonstrated in multiple studies, but treatmen …
Therapeutic options include destructive modalities (i.e., cryosurgery, curettage) or topical fluorouracil treatment. The effic …
Topical 5-fluorouracil 1% for moderate to extensive ocular surface squamous neoplasia in 73 consecutive patients: Primary versus secondary treatment.
Leventer I, Singh H, Pashaee B, Raimondo CD, Khakh CK, Martin JL, Acharya B, Zhang Q, Lally SE, Shields CL. Leventer I, et al. Asia Pac J Ophthalmol (Phila). 2024 Mar-Apr;13(2):100052. doi: 10.1016/j.apjo.2024.100052. Epub 2024 Mar 21. Asia Pac J Ophthalmol (Phila). 2024. PMID: 38521390 Free article.
IMPORTANCE: Ocular surface squamous neoplasia (OSSN) is a spectrum of malignancies that generally includes conjunctival intraepithelial neoplasia (CIN) and squamous cell carcinoma (SCC). OSSN can be treated with topical therapies including interferon alpha-2b (IFN), mitomy …
IMPORTANCE: Ocular surface squamous neoplasia (OSSN) is a spectrum of malignancies that generally includes conjunctival intraepithelial neop …
Topical application of 5-fluorouracil 5 percent cream associated with severe neutropenia: discussion of a case and review of systemic reactions after topical treatment with 5-fluorouracil.
Cohen PR. Cohen PR. Dermatol Online J. 2018 Apr 15;24(4):13030/qt974797j7. Dermatol Online J. 2018. PMID: 29906006 Free article. Review.
5-fluorouracil, a fluoropyrimidine antineoplastic drug, is used to topically treat actinic keratoses. Local skin reactions to the medication are common and anticipated. However, severe adverse events from topical 5-fluorouracil are rare and unexpected. …
5-fluorouracil, a fluoropyrimidine antineoplastic drug, is used to topically treat actinic keratoses. Local skin reactions to …
1,694 results