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211 results

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Page 1
Guidelines of care for the management of acne vulgaris.
Reynolds RV, Yeung H, Cheng CE, Cook-Bolden F, Desai SR, Druby KM, Freeman EE, Keri JE, Stein Gold LF, Tan JKL, Tollefson MM, Weiss JS, Wu PA, Zaenglein AL, Han JM, Barbieri JS. Reynolds RV, et al. J Am Acad Dermatol. 2024 May;90(5):1006.e1-1006.e30. doi: 10.1016/j.jaad.2023.12.017. Epub 2024 Jan 30. J Am Acad Dermatol. 2024. PMID: 38300170
Strong recommendations are made for benzoyl peroxide, topical retinoids, topical antibiotics, and oral doxycycline. Oral isotretinoin is strongly recommended for acne that is severe, causing psychosocial burden or scarring, or failing standard oral or topical …
Strong recommendations are made for benzoyl peroxide, topical retinoids, topical antibiotics, and oral doxycycline. Oral isotr …
The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review.
Wang C, Du Y, Bi L, Lin X, Zhao M, Fan W. Wang C, et al. Clin Cosmet Investig Dermatol. 2023 Mar 9;16:603-612. doi: 10.2147/CCID.S398950. eCollection 2023. Clin Cosmet Investig Dermatol. 2023. PMID: 36923692 Free PMC article. Review.
Dosage forms for topical spironolactone use include gels of 1% and solutions of 5% twice daily. Both oral and topical spironolactone have been shown efficacy for alopecia recovery, but topical use has significantly fewer side effects and is suit …
Dosage forms for topical spironolactone use include gels of 1% and solutions of 5% twice daily. Both oral and topical …
Management of Acne Vulgaris: A Review.
Eichenfield DZ, Sprague J, Eichenfield LF. Eichenfield DZ, et al. JAMA. 2021 Nov 23;326(20):2055-2067. doi: 10.1001/jama.2021.17633. JAMA. 2021. PMID: 34812859 Review.
Although most acne does not require specific medical evaluation, medical workup is sometimes warranted. Topical therapies such as retinoids (eg, tretinoin, adapalene), benzoyl peroxide, azelaic acid, and/or combinations of topical agents are first-line treatments. . …
Although most acne does not require specific medical evaluation, medical workup is sometimes warranted. Topical therapies such as ret …
Guidelines of care for the management of acne vulgaris.
Zaenglein AL, Pathy AL, Schlosser BJ, Alikhan A, Baldwin HE, Berson DS, Bowe WP, Graber EM, Harper JC, Kang S, Keri JE, Leyden JJ, Reynolds RV, Silverberg NB, Stein Gold LF, Tollefson MM, Weiss JS, Dolan NC, Sagan AA, Stern M, Boyer KM, Bhushan R. Zaenglein AL, et al. J Am Acad Dermatol. 2016 May;74(5):945-73.e33. doi: 10.1016/j.jaad.2015.12.037. Epub 2016 Feb 17. J Am Acad Dermatol. 2016. PMID: 26897386 Free article. Review.
This evidence-based guideline addresses important clinical questions that arise in its management. Issues from grading of acne to the topical and systemic management of the disease are reviewed. Suggestions on use are provided based on available evidence....
This evidence-based guideline addresses important clinical questions that arise in its management. Issues from grading of acne to the top …
Managing acne vulgaris: an update.
Santer M, Burden-Teh E, Ravenscroft J. Santer M, et al. Drug Ther Bull. 2023 Dec 27;62(1):6-10. doi: 10.1136/dtb.2023.000051. Drug Ther Bull. 2023. PMID: 38154809 Free PMC article. Review.
While sometimes a transient problem, acne may persist for many years and often leads to permanent scars or pigment changes. Guidelines unanimously advise topical treatments as first-line, although differ in recommending either topical benzoyl peroxide or topical …
While sometimes a transient problem, acne may persist for many years and often leads to permanent scars or pigment changes. Guidelines unani …
Role of topical spironolactone in the treatment of acne: A systematic review of clinical trials-Does this therapy open a path towards favorable outcomes?
Rehan ST, Khan Z, Abbas S, Imran L, Munir S, Tahir MJ, Kheljee AZ, Eljack MMF, Ahmed A. Rehan ST, et al. J Dermatol. 2023 Feb;50(2):166-174. doi: 10.1111/1346-8138.16637. Epub 2022 Nov 22. J Dermatol. 2023. PMID: 36412248
Recent evidence shows that spironolactone in topical form has similar efficacy to its oral form with comparatively fewer adverse events associated with its use. ...Topical spironolactone yields better results than other first-line treatments for acne a …
Recent evidence shows that spironolactone in topical form has similar efficacy to its oral form with comparatively fewer adver …
The efficacy of Topical Clascoterone versus systematic spironolactone for treatment of acne vulgaris: A systematic review and network meta-analysis.
Basendwh MA, Alharbi AA, Bukhamsin SA, Abdulwahab RA, Alaboud SA. Basendwh MA, et al. PLoS One. 2024 May 30;19(5):e0298155. doi: 10.1371/journal.pone.0298155. eCollection 2024. PLoS One. 2024. PMID: 38814916 Free PMC article.
OBJECTIVES: This study aimed to evaluate the effectiveness of topical clascoterone (TC) compared to oral spironolactone for acne vulgaris treatment. ...These results suggest that both TC and Spironolactone could be beneficial in treating patients with acne vu …
OBJECTIVES: This study aimed to evaluate the effectiveness of topical clascoterone (TC) compared to oral spironolactone for ac …
Oral and topical spironolactone in acne treatment: A meta-analysis of effectiveness and safety.
AlEdani EM, Abo Zeid M, Khalefa K, Abbas AW, Aboali AA, Raslan HAS, Shakhatreh Z, Yakout IA, Elrosasy A. AlEdani EM, et al. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jul;398(7):9005-9019. doi: 10.1007/s00210-025-03840-6. Epub 2025 Jan 29. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 39878821
This systematic review and meta-analysis aims to assess the safety and efficacy of oral and topical spironolactone in acne treatment. Following PRISMA guidelines, a complete search of five databases yielded seven eligible studies (643 individuals) that compared s …
This systematic review and meta-analysis aims to assess the safety and efficacy of oral and topical spironolactone in acne tre …
Management of androgenic alopecia: a systematic review of the literature.
Rosenthal A, Conde G, Greco JF, Gharavi NM. Rosenthal A, et al. J Cosmet Laser Ther. 2024 Jan-Jun;26(1-4):1-16. doi: 10.1080/14764172.2024.2362126. Epub 2024 Jun 9. J Cosmet Laser Ther. 2024. PMID: 38852607
We aimed to determine the efficacy of the various available oral, topical, and procedural treatment options for hair loss in individuals with androgenic alopecia. ...We demonstrate that many over the counter (e.g. topical minoxidil, supplements, low-level light trea …
We aimed to determine the efficacy of the various available oral, topical, and procedural treatment options for hair loss in individu …
A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds.
Dereiah S, Ghori MU, Conway BR. Dereiah S, et al. Pharmaceutics. 2024 Dec 27;17(1):27. doi: 10.3390/pharmaceutics17010027. Pharmaceutics. 2024. PMID: 39861676 Free PMC article. Review.
Background/Objectives: Spironolactone (SP), an aldosterone inhibitor widely used to treat androgen-dependent disorders such as acne, hirsutism, and alopecia, has demonstrated therapeutic potential in both oral and topical formulations. ...Additionally, one study on …
Background/Objectives: Spironolactone (SP), an aldosterone inhibitor widely used to treat androgen-dependent disorders such as acne, …
211 results