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A new approach to drug discovery: high-throughput screening of microbial natural extracts against Aspergillus fumigatus using resazurin.
Monteiro MC, de la Cruz M, Cantizani J, Moreno C, Tormo JR, Mellado E, De Lucas JR, Asensio F, Valiante V, Brakhage AA, Latgé JP, Genilloud O, Vicente F. Monteiro MC, et al. Among authors: tormo jr. J Biomol Screen. 2012 Apr;17(4):542-9. doi: 10.1177/1087057111433459. Epub 2012 Jan 10. J Biomol Screen. 2012. PMID: 22233645
High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease.
Annang F, Pérez-Moreno G, García-Hernández R, Cordon-Obras C, Martín J, Tormo JR, Rodríguez L, de Pedro N, Gómez-Pérez V, Valente M, Reyes F, Genilloud O, Vicente F, Castanys S, Ruiz-Pérez LM, Navarro M, Gamarro F, González-Pacanowska D. Annang F, et al. Among authors: tormo jr. J Biomol Screen. 2015 Jan;20(1):82-91. doi: 10.1177/1087057114555846. Epub 2014 Oct 20. J Biomol Screen. 2015. PMID: 25332350
High-content screening of natural products reveals novel nuclear export inhibitors.
Cautain B, de Pedro N, Murillo Garzón V, Muñoz de Escalona M, González Menéndez V, Tormo JR, Martin J, El Aouad N, Reyes F, Asensio F, Genilloud O, Vicente F, Link W. Cautain B, et al. Among authors: tormo jr. J Biomol Screen. 2014 Jan;19(1):57-65. doi: 10.1177/1087057113501389. Epub 2013 Sep 17. J Biomol Screen. 2014. PMID: 24045581
Discovery of New Compounds Active against Plasmodium falciparum by High Throughput Screening of Microbial Natural Products.
Pérez-Moreno G, Cantizani J, Sánchez-Carrasco P, Ruiz-Pérez LM, Martín J, El Aouad N, Pérez-Victoria I, Tormo JR, González-Menendez V, González I, de Pedro N, Reyes F, Genilloud O, Vicente F, González-Pacanowska D. Pérez-Moreno G, et al. Among authors: tormo jr. PLoS One. 2016 Jan 6;11(1):e0145812. doi: 10.1371/journal.pone.0145812. eCollection 2016. PLoS One. 2016. PMID: 26735308 Free PMC article.
High-Throughput Screening Platform for the Discovery of New Immunomodulator Molecules from Natural Product Extract Libraries.
Pérez Del Palacio J, Díaz C, de la Cruz M, Annang F, Martín J, Pérez-Victoria I, González-Menéndez V, de Pedro N, Tormo JR, Algieri F, Rodriguez-Nogales A, Rodríguez-Cabezas ME, Reyes F, Genilloud O, Vicente F, Gálvez J. Pérez Del Palacio J, et al. Among authors: tormo jr. J Biomol Screen. 2016 Jul;21(6):567-78. doi: 10.1177/1087057116635517. Epub 2016 Mar 8. J Biomol Screen. 2016. PMID: 26962874
Design of High-Throughput Screening of Natural Extracts to Identify Molecules Bypassing Primary Coenzyme Q Deficiency in Saccharomyces cerevisiae.
Berenguel Hernández AM, de la Cruz M, Alcázar-Fabra M, Prieto-Rodríguez A, Sánchez-Cuesta A, Martin J, Tormo JR, Rodríguez-Aguilera JC, Cortés-Rodríguez AB, Navas P, Reyes F, Vicente F, Genilloud O, Santos-Ocaña C. Berenguel Hernández AM, et al. Among authors: tormo jr. SLAS Discov. 2020 Mar;25(3):299-309. doi: 10.1177/2472555219877185. Epub 2019 Nov 21. SLAS Discov. 2020. PMID: 31751168 Free article.
Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010).
Valiante V, Monteiro MC, Martín J, Altwasser R, El Aouad N, González I, Kniemeyer O, Mellado E, Palomo S, de Pedro N, Pérez-Victoria I, Tormo JR, Vicente F, Reyes F, Genilloud O, Brakhage AA. Valiante V, et al. Among authors: tormo jr. Antimicrob Agents Chemother. 2015 Sep;59(9):5145-53. doi: 10.1128/AAC.00683-15. Epub 2015 Jun 8. Antimicrob Agents Chemother. 2015. PMID: 26055366 Free PMC article.
112 results