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The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition.
Brandi J, Cecconi D, Cordani M, Torrens-Mas M, Pacchiana R, Dalla Pozza E, Butera G, Manfredi M, Marengo E, Oliver J, Roca P, Dando I, Donadelli M. Brandi J, et al. Free Radic Biol Med. 2016 Dec;101:305-316. doi: 10.1016/j.freeradbiomed.2016.10.499. Epub 2016 Oct 27. Free Radic Biol Med. 2016. PMID: 27989750
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells.
Cordani M, Butera G, Dando I, Torrens-Mas M, Butturini E, Pacchiana R, Oppici E, Cavallini C, Gasperini S, Tamassia N, Nadal-Serrano M, Coan M, Rossi D, Gaidano G, Caraglia M, Mariotto S, Spizzo R, Roca P, Oliver J, Scupoli MT, Donadelli M. Cordani M, et al. Br J Cancer. 2018 Oct;119(8):994-1008. doi: 10.1038/s41416-018-0288-2. Epub 2018 Oct 15. Br J Cancer. 2018. PMID: 30318520 Free PMC article.
SIRT3: Oncogene and Tumor Suppressor in Cancer.
Torrens-Mas M, Oliver J, Roca P, Sastre-Serra J. Torrens-Mas M, et al. Cancers (Basel). 2017 Jul 12;9(7):90. doi: 10.3390/cancers9070090. Cancers (Basel). 2017. PMID: 28704962 Free PMC article. Review.
26 results