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Inhibition of choline metabolism in an angioimmunoblastic T-cell lymphoma preclinical model reveals a new metabolic vulnerability as possible target for treatment.
Krug A, Tosolini M, Madji Hounoum B, Fournié JJ, Geiger R, Pecoraro M, Emond P, Gaulard P, Lemonnier F, Ricci JE, Verhoeyen E. Krug A, et al. Among authors: tosolini m. J Exp Clin Cancer Res. 2024 Feb 6;43(1):43. doi: 10.1186/s13046-024-02952-w. J Exp Clin Cancer Res. 2024. PMID: 38321568 Free PMC article.
TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation.
Pichler AC, Carrié N, Cuisinier M, Ghazali S, Voisin A, Axisa PP, Tosolini M, Mazzotti C, Golec DP, Maheo S, do Souto L, Ekren R, Blanquart E, Lemaitre L, Feliu V, Joubert MV, Cannons JL, Guillerey C, Avet-Loiseau H, Watts TH, Salomon BL, Joffre O, Grinberg-Bleyer Y, Schwartzberg PL, Lucca LE, Martinet L. Pichler AC, et al. Among authors: tosolini m. Immunity. 2023 Jul 11;56(7):1631-1648.e10. doi: 10.1016/j.immuni.2023.06.007. Epub 2023 Jun 30. Immunity. 2023. PMID: 37392737 Free PMC article.
66 results