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GenAge: a genomic and proteomic network map of human ageing.
de Magalhães JP, Toussaint O. de Magalhães JP, et al. FEBS Lett. 2004 Jul 30;571(1-3):243-7. doi: 10.1016/j.febslet.2004.07.006. FEBS Lett. 2004. PMID: 15280050
Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase.
de Magalhães JP, Chainiaux F, de Longueville F, Mainfroid V, Migeot V, Marcq L, Remacle J, Salmon M, Toussaint O. de Magalhães JP, et al. Exp Gerontol. 2004 Sep;39(9):1379-89. doi: 10.1016/j.exger.2004.06.004. Exp Gerontol. 2004. PMID: 15489061
Transcriptomic biomarkers of human ageing in peripheral blood mononuclear cell total RNA.
Vo TK, Godard P, de Saint-Hubert M, Morrhaye G, Bauwens E, Debacq-Chainiaux F, Glupczynski Y, Swine C, Geenen V, Martens HJ, Toussaint O. Vo TK, et al. Exp Gerontol. 2010 Mar;45(3):188-94. doi: 10.1016/j.exger.2009.12.001. Epub 2009 Dec 6. Exp Gerontol. 2010. PMID: 19995600
Upregulation of annexin A2 in H(2)O(2)-induced premature senescence as evidenced by 2D-DIGE proteome analysis.
Chrétien A, Delaive E, Dieu M, Demazy C, Ninane N, Raes M, Toussaint O. Chrétien A, et al. Exp Gerontol. 2008 Apr;43(4):353-9. doi: 10.1016/j.exger.2008.01.003. Epub 2008 Jan 18. Exp Gerontol. 2008. PMID: 18289818
Human diploid fibroblasts undergo premature senescence after treatment with sublethal concentration of H(2)O(2). We report the first proteomic study of microsomal proteins in the context of H(2)O(2)-induced premature senescence by using 2D-DIGE approach. Twelve diff …
Human diploid fibroblasts undergo premature senescence after treatment with sublethal concentration of H(2)O(2). We report the first …
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays.
Pascal T, Debacq-Chainiaux F, Chrétien A, Bastin C, Dabée AF, Bertholet V, Remacle J, Toussaint O. Pascal T, et al. FEBS Lett. 2005 Jul 4;579(17):3651-9. doi: 10.1016/j.febslet.2005.05.056. FEBS Lett. 2005. PMID: 15963989
No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.
de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, Toussaint O. de Magalhães JP, et al. Ann N Y Acad Sci. 2004 Jun;1019:375-8. doi: 10.1196/annals.1297.066. Ann N Y Acad Sci. 2004. PMID: 15247048 Review.
Normal human diploid fibroblasts (HDFs) exposed to a single H(2)O(2) subcytotoxic stress display features of premature senescence, termed stress-induced premature senescence (SIPS). ...Intriguingly, the percentage of positive cells did not increase with the dose of H(2) …
Normal human diploid fibroblasts (HDFs) exposed to a single H(2)O(2) subcytotoxic stress display features of premature senescence, te …
How bioinformatics can help reverse engineer human aging.
de Magalhães JP, Toussaint O. de Magalhães JP, et al. Ageing Res Rev. 2004 Apr;3(2):125-41. doi: 10.1016/j.arr.2003.08.006. Ageing Res Rev. 2004. PMID: 15177050 Review.
Role of the PLA2-independent peroxiredoxin VI activity in the survival of immortalized fibroblasts exposed to cytotoxic oxidative stress.
Salmon M, Dedessus Le Moutier J, Wenders F, Chiarizia S, Eliaers F, Remacle J, Royer V, Pascal T, Toussaint O. Salmon M, et al. FEBS Lett. 2004 Jan 16;557(1-3):26-32. doi: 10.1016/s0014-5793(03)01437-6. FEBS Lett. 2004. PMID: 14741336
Normal brain aging: a commentary.
Toussaint O. Toussaint O. Neurobiol Aging. 2003 May-Jun;24 Suppl 1:S129-30; discussion S131. doi: 10.1016/s0197-4580(03)00052-6. Neurobiol Aging. 2003. PMID: 12829121
Exposure of human skin diploid fibroblasts to repeated subcytotoxic doses of ultraviolet-B induces the overexpression of transforming growth factor-beta1 mRNA.
Chainiaux F, Remacle J, Toussaint O. Chainiaux F, et al. Ann N Y Acad Sci. 2002 Nov;973:44-8. doi: 10.1111/j.1749-6632.2002.tb04603.x. Ann N Y Acad Sci. 2002. PMID: 12485831
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