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18 results
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Mycobacterium tuberculosis High-Throughput Screening.
White EL, Tower NA, Rasmussen L. White EL, et al. Among authors: tower na. Methods Mol Biol. 2016;1439:181-95. doi: 10.1007/978-1-4939-3673-1_12. Methods Mol Biol. 2016. PMID: 27316996
A BSL-4 high-throughput screen identifies sulfonamide inhibitors of Nipah virus.
Tigabu B, Rasmussen L, White EL, Tower N, Saeed M, Bukreyev A, Rockx B, LeDuc JW, Noah JW. Tigabu B, et al. Assay Drug Dev Technol. 2014 Apr;12(3):155-61. doi: 10.1089/adt.2013.567. Assay Drug Dev Technol. 2014. PMID: 24735442 Free PMC article.
Adapting high-throughput screening methods and assays for biocontainment laboratories.
Rasmussen L, Tigabu B, White EL, Bostwick R, Tower N, Bukreyev A, Rockx B, LeDuc JW, Noah JW. Rasmussen L, et al. Assay Drug Dev Technol. 2015 Jan-Feb;13(1):44-54. doi: 10.1089/adt.2014.617. Assay Drug Dev Technol. 2015. PMID: 25710545 Free PMC article. Review.
Discovery of novel inhibitors of ribosome biogenesis by innovative high throughput screening strategies.
Scull CE, Zhang Y, Tower N, Rasmussen L, Padmalayam I, Hunter R, Zhai L, Bostwick R, Schneider DA. Scull CE, et al. Biochem J. 2019 Aug 9;476(15):2209-2219. doi: 10.1042/BCJ20190207. Biochem J. 2019. PMID: 31341008 Free PMC article.
High-throughput screening identifies a bisphenol inhibitor of SV40 large T antigen ATPase activity.
Seguin SP, Evans CW, Nebane-Akah M, McKellip S, Ananthan S, Tower NA, Sosa M, Rasmussen L, White EL, Maki BE, Matharu DS, Golden JE, Aubé J, Brodsky JL, Noah JW. Seguin SP, et al. J Biomol Screen. 2012 Feb;17(2):194-203. doi: 10.1177/1087057111421630. Epub 2011 Sep 23. J Biomol Screen. 2012. PMID: 21948801 Free PMC article.
(S)-N-(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a small molecule inhibitor probe for the study of respiratory syncytial virus infection.
Moore BP, Chung DH, Matharu DS, Golden JE, Maddox C, Rasmussen L, Noah JW, Sosa MI, Ananthan S, Tower NA, White EL, Jia F, Prisinzano TE, Aubé J, Jonsson CB, Severson WE. Moore BP, et al. J Med Chem. 2012 Oct 25;55(20):8582-7. doi: 10.1021/jm300612z. Epub 2012 Oct 16. J Med Chem. 2012. PMID: 23043370 Free PMC article.
High-throughput screening and Bayesian machine learning for copper-dependent inhibitors of Staphylococcus aureus.
Dalecki AG, Zorn KM, Clark AM, Ekins S, Narmore WT, Tower N, Rasmussen L, Bostwick R, Kutsch O, Wolschendorf F. Dalecki AG, et al. Metallomics. 2019 Mar 20;11(3):696-706. doi: 10.1039/c8mt00342d. Metallomics. 2019. PMID: 30839007 Free PMC article.
Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.
Chung DH, Jonsson CB, Tower NA, Chu YK, Sahin E, Golden JE, Noah JW, Schroeder CE, Sotsky JB, Sosa MI, Cramer DE, McKellip SN, Rasmussen L, White EL, Schmaljohn CS, Julander JG, Smith JM, Filone CM, Connor JH, Sakurai Y, Davey RA. Chung DH, et al. Among authors: tower na. PLoS Pathog. 2014 Jun 26;10(6):e1004213. doi: 10.1371/journal.ppat.1004213. eCollection 2014 Jun. PLoS Pathog. 2014. PMID: 24967809 Free PMC article.
Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus.
Schroeder CE, Yao T, Sotsky J, Smith RA, Roy S, Chu YK, Guo H, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, Smith LH, White EL, Aubé J, Jonsson CB, Chung D, Golden JE. Schroeder CE, et al. Among authors: tower na. J Med Chem. 2014 Oct 23;57(20):8608-21. doi: 10.1021/jm501203v. Epub 2014 Oct 7. J Med Chem. 2014. PMID: 25244572 Free PMC article.
Lifting the mask: identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis.
Goller CC, Arshad M, Noah JW, Ananthan S, Evans CW, Nebane NM, Rasmussen L, Sosa M, Tower NA, White EL, Neuenswander B, Porubsky P, Maki BE, Rogers SA, Schoenen F, Seed PC. Goller CC, et al. Among authors: tower na. PLoS One. 2014 Jul 1;9(7):e96054. doi: 10.1371/journal.pone.0096054. eCollection 2014. PLoS One. 2014. PMID: 24983234 Free PMC article.
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