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239 results

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Role of Toxoplasma gondii IgG Avidity Testing in Discriminating between Acute and Chronic Toxoplasmosis in Pregnancy.
Teimouri A, Mohtasebi S, Kazemirad E, Keshavarz H. Teimouri A, et al. J Clin Microbiol. 2020 Aug 24;58(9):e00505-20. doi: 10.1128/JCM.00505-20. Print 2020 Aug 24. J Clin Microbiol. 2020. PMID: 32321784 Free PMC article. Review.
This parameter matures gradually within 6 months of the primary infection. A high Toxo IgG avidity index allows a recent infection (less than 4 months) to be excluded, whereas a low Toxo IgG avidity index indicates a probable recent infection with no e …
This parameter matures gradually within 6 months of the primary infection. A high Toxo IgG avidity index allows a recent infec …
Toxoplasma gondii-specific IgG avidity testing in pregnant women.
Garnaud C, Fricker-Hidalgo H, Evengård B, Álvarez-Martínez MJ, Petersen E, Kortbeek LM, Robert-Gangneux F, Villena I, Costache C, Paul M, Meroni V, Guy E, Chiodini PL, Brenier-Pinchart MP, Pelloux H; under the auspices of the ESGCP of ESCMID. Garnaud C, et al. Clin Microbiol Infect. 2020 Sep;26(9):1155-1160. doi: 10.1016/j.cmi.2020.04.014. Epub 2020 Apr 22. Clin Microbiol Infect. 2020. PMID: 32334096 Free article. Review.
It is therefore important to distinguish between recent and past infection when both T. gondii-specific IgM and IgG are detected in a single serum in pregnant women. Toxoplasma gondii-specific IgG avidity testing is an essential tool to help to date th …
It is therefore important to distinguish between recent and past infection when both T. gondii-specific IgM and IgG are detected in a …
Prevalence, risk factors, diagnosis and outcomes of Toxoplasma gondii infection in pregnancy: A review.
Walana W, Odai SA, Tamomh AG. Walana W, et al. Parasitol Int. 2026 Feb;110:103143. doi: 10.1016/j.parint.2025.103143. Epub 2025 Aug 14. Parasitol Int. 2026. PMID: 40818495 Review.
BACKGROUND: Toxoplasmosis, caused by the zoonotic protozoan Toxoplasma gondii, poses substantial risks during pregnancy, including adverse maternal and neonatal outcomes. ...Diagnosis primarily relied on serological assays (IgG/IgM ELISA), augmented by molecu …
BACKGROUND: Toxoplasmosis, caused by the zoonotic protozoan Toxoplasma gondii, poses substantial risks during pregnancy, inclu …
Toxoplasmosis.
Petersen E. Petersen E. Semin Fetal Neonatal Med. 2007 Jun;12(3):214-23. doi: 10.1016/j.siny.2007.01.011. Epub 2007 Feb 23. Semin Fetal Neonatal Med. 2007. PMID: 17321812 Review.
Infections with Toxoplasma gondii occur worldwide, but are especially prevalent in Europe, South America and Africa. The primary problem for the diagnosis of T. gondii infection is long-lasting IgM-antibodies, thus the presence of T. gondii-specific IgM-antibodies do not n …
Infections with Toxoplasma gondii occur worldwide, but are especially prevalent in Europe, South America and Africa. The primary prob …
Evaluation of Toxoplasma gondii IgG avidity assays through a comparison of IgM serostatus.
Ikuta K, Kanno R, Bessho T, Koshizuka T, Suzutani T. Ikuta K, et al. Diagn Microbiol Infect Dis. 2023 Apr;105(4):115901. doi: 10.1016/j.diagmicrobio.2023.115901. Epub 2023 Jan 18. Diagn Microbiol Infect Dis. 2023. PMID: 36889215 Free article.
Primary Toxoplasma gondii (T. gondii) infection during pregnancy could result in congenital disease with severe clinical complications. ...Here, we evaluated and compared the performance of T. gondii IgG avidity assays as confirmed by T. gondii IgM ser …
Primary Toxoplasma gondii (T. gondii) infection during pregnancy could result in congenital disease with severe clinical compl …
Persistent Low Toxoplasma IgG Avidity Is Common in Pregnancy: Experience from Antenatal Testing in Norway.
Findal G, Stray-Pedersen B, Holter EK, Berge T, Jenum PA. Findal G, et al. PLoS One. 2015 Dec 29;10(12):e0145519. doi: 10.1371/journal.pone.0145519. eCollection 2015. PLoS One. 2015. PMID: 26714282 Free PMC article.
The parasite Toxoplasma gondii might harm the fetus if a woman is infected during pregnancy. IgG seroconversion and significant increase in IgG antibody amount in pregnancy indicates maternal infection. Presence of toxoplasma immunoglobul …
The parasite Toxoplasma gondii might harm the fetus if a woman is infected during pregnancy. IgG seroconversion and sig …
IgG avidity test for the diagnosis of acute Toxoplasma gondii infection in early pregnancy.
Pour Abolghasem S, Bonyadi MR, Babaloo Z, Porhasan A, Nagili B, Gardashkhani OA, Salehi P, Hashemi M, Varshoghi M, Gaffari GO. Pour Abolghasem S, et al. Iran J Immunol. 2011 Dec;8(4):251-5. doi: 10.22034/iji.2011.17033. Iran J Immunol. 2011. PMID: 22201623 Free article.
Anti-toxoplasma IgG, IgM and IgG avidity were evaluated by ELISA method. RESULTS: The patients were categorized into three groups as follows: Group A, 124 cases; IgG+, IgM+, 55.1%; group B, 99 cases; IgG+, IgM-, 44%; and group C, 2 cases; …
Anti-toxoplasma IgG, IgM and IgG avidity were evaluated by ELISA method. RESULTS: The patients were categorized …
Diagnostic accuracy of adjusted low IgG avidity index to predict acute Toxoplasma gondii infection in the first trimester of pregnancy.
Skvarc M. Skvarc M. Folia Parasitol. 2022 Oct 19;69:2022.023. doi: 10.14411/fp.2022.023. Folia Parasitol. 2022. PMID: 36314892 Free article.

If an IgG avidity index above 0.11 is measured in a woman's serum and she is in the first trimester of pregnancy, then a odds ratio (OR) for acute infection with T. gondii is below 1 (OR 0.11, 95% CI 0.05-0.25, P < 0.0001). If we measure IgG avid

…
If an IgG avidity index above 0.11 is measured in a woman's serum and she is in the first trimester of pregnancy, then …
Toxoplasma gondii IgG avidity for the diagnosis of primary infection in pregnant women: Comparison between chemiluminescent microparticle immunoassay and enzyme-linked immunosorbent assay.
Ota H, Yamada H, Wada S, Tanimura K, Deguchi M, Uchida A, Nishikawa A. Ota H, et al. J Infect Chemother. 2024 May;30(5):434-438. doi: 10.1016/j.jiac.2023.11.019. Epub 2023 Nov 23. J Infect Chemother. 2024. PMID: 38000499
Their stored sera were used for T. gondii IgG avidity measurements by CMIA. RESULTS: In CMIA, 72 (67.9%) women had low (<50%), 12 (11.3%) had borderline (50%-59.9%), and 22 (20.8%) had high ( 60%) IgG avidity. ...All three cases with congenital T. g …
Their stored sera were used for T. gondii IgG avidity measurements by CMIA. RESULTS: In CMIA, 72 (67.9%) women had low (<50 …
Determination of Low IgG Class Antibody Avidity Percentage by IgM Levels Specific to Toxoplasma Gondii.
Bakir A, Guney M. Bakir A, et al. Clin Lab. 2022 Aug 1;68(8). doi: 10.7754/Clin.Lab.2021.211112. Clin Lab. 2022. PMID: 35975508
In this study, we aimed to evaluate whether the anti-T. gondii IgM antibody index threshold value could be a predictive factor in the estimation of low avidity and its use in improving the diagnosis of early toxoplasma infection. METHODS: Anti-T. gondii IgM, IgG …
In this study, we aimed to evaluate whether the anti-T. gondii IgM antibody index threshold value could be a predictive factor in the estima …
239 results