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The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.
Niemann A, Huber N, Wagner KM, Somandin C, Horn M, Lebrun-Julien F, Angst B, Pereira JA, Halfter H, Welzl H, Feltri ML, Wrabetz L, Young P, Wessig C, Toyka KV, Suter U. Niemann A, et al. Among authors: toyka kv. Brain. 2014 Mar;137(Pt 3):668-82. doi: 10.1093/brain/awt371. Epub 2014 Jan 29. Brain. 2014. PMID: 24480485 Free PMC article.
An animal model for Charcot-Marie-Tooth disease type 4B1.
Bonneick S, Boentert M, Berger P, Atanasoski S, Mantei N, Wessig C, Toyka KV, Young P, Suter U. Bonneick S, et al. Among authors: toyka kv. Hum Mol Genet. 2005 Dec 1;14(23):3685-95. doi: 10.1093/hmg/ddi400. Epub 2005 Oct 25. Hum Mol Genet. 2005. PMID: 16249189
Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function.
Gerber D, Ghidinelli M, Tinelli E, Somandin C, Gerber J, Pereira JA, Ommer A, Figlia G, Miehe M, Nägeli LG, Suter V, Tadini V, Sidiropoulos PN, Wessig C, Toyka KV, Suter U. Gerber D, et al. Among authors: toyka kv. Elife. 2019 Jan 16;8:e42404. doi: 10.7554/eLife.42404. Elife. 2019. PMID: 30648534 Free PMC article.
Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2.
Tersar K, Boentert M, Berger P, Bonneick S, Wessig C, Toyka KV, Young P, Suter U. Tersar K, et al. Among authors: toyka kv. Hum Mol Genet. 2007 Dec 15;16(24):2991-3001. doi: 10.1093/hmg/ddm257. Epub 2007 Sep 12. Hum Mol Genet. 2007. PMID: 17855448
Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy.
Pereira JA, Gerber J, Ghidinelli M, Gerber D, Tortola L, Ommer A, Bachofner S, Santarella F, Tinelli E, Lin S, Rüegg MA, Kopf M, Toyka KV, Suter U. Pereira JA, et al. Among authors: toyka kv. Hum Mol Genet. 2020 May 28;29(8):1253-1273. doi: 10.1093/hmg/ddaa034. Hum Mol Genet. 2020. PMID: 32129442 Free PMC article.
483 results