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uPAR isoform 2 forms a dimer and induces severe kidney disease in mice.
Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, Dibartolo S, Hägele S, Peev V, Hayek SS, Cimbaluk DJ, Tracy M, Klein J, Sever S, Shattil SJ, Arnaout MA, Reiser J. Wei C, et al. Among authors: tracy m. J Clin Invest. 2019 Apr 2;129(5):1946-1959. doi: 10.1172/JCI124793. eCollection 2019 Apr 2. J Clin Invest. 2019. PMID: 30730305 Free PMC article.
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, Sever S, Sykes DB, Scadden DT, Reiser J. Hahm E, et al. Among authors: tracy m. Nat Med. 2017 Jan;23(1):100-106. doi: 10.1038/nm.4242. Epub 2016 Dec 12. Nat Med. 2017. PMID: 27941791 Free PMC article.
A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.
Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J. Hayek SS, et al. Among authors: tracy m. Nat Med. 2017 Aug;23(8):945-953. doi: 10.1038/nm.4362. Epub 2017 Jun 26. Nat Med. 2017. PMID: 28650456 Free PMC article.
Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children.
Schaefer F, Trachtman H, Wühl E, Kirchner M, Hayek SS, Anarat A, Duzova A, Mir S, Paripovic D, Yilmaz A, Lugani F, Arbeiter K, Litwin M, Oh J, Matteucci MC, Gellermann J, Wygoda S, Jankauskiene A, Klaus G, Dusek J, Testa S, Zurowska A, Caldas Afonso A, Tracy M, Wei C, Sever S, Smoyer W, Reiser J; ESCAPE Trial Consortium and the 4C Study Group. Schaefer F, et al. Among authors: tracy m. JAMA Pediatr. 2017 Nov 6;171(11):e172914. doi: 10.1001/jamapediatrics.2017.2914. Epub 2017 Nov 6. JAMA Pediatr. 2017. PMID: 28873129 Free PMC article.
Soluble Urokinase-Type Plasminogen Activator Receptor in Black Americans with CKD.
Luo S, Coresh J, Tin A, Rebholz CM, Chen TK, Hayek SS, Tracy M, Lipkowitz MS, Appel LJ, Levey AS, Inker LA, Reiser J, Grams ME. Luo S, et al. Among authors: tracy m. Clin J Am Soc Nephrol. 2018 Jul 6;13(7):1013-1021. doi: 10.2215/CJN.13631217. Epub 2018 Jun 14. Clin J Am Soc Nephrol. 2018. PMID: 29903900 Free PMC article.
Pearls and Purple: The Dawn of a Modern Age.
Tracy M, Volgman AS. Tracy M, et al. J Am Heart Assoc. 2021 Feb;10(5):e020903. doi: 10.1161/JAHA.121.020903. Epub 2021 Feb 23. J Am Heart Assoc. 2021. PMID: 33618550 Free PMC article. No abstract available.
571 results