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Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis.
Corrias MV, Parodi S, Tchirkov A, Lammens T, Vicha A, Pasqualini C, Träger C, Yáñez Y, Dallorso S, Varesio L, Luksch R, Laureys G, Valteau-Couanet D, Canete A, Pöetschger U, Ladenstein R, Burchill SA. Corrias MV, et al. Among authors: trager c. Pediatr Blood Cancer. 2018 Jul;65(7):e27052. doi: 10.1002/pbc.27052. Epub 2018 Mar 30. Pediatr Blood Cancer. 2018. PMID: 29603574 Free article. Clinical Trial.
MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling.
Dzieran J, Rodriguez Garcia A, Westermark UK, Henley AB, Eyre Sánchez E, Träger C, Johansson HJ, Lehtiö J, Arsenian-Henriksson M. Dzieran J, et al. Among authors: trager c. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1229-E1238. doi: 10.1073/pnas.1710901115. Epub 2018 Jan 26. Proc Natl Acad Sci U S A. 2018. PMID: 29374092 Free PMC article.
Emergence of new ALK mutations at relapse of neuroblastoma.
Schleiermacher G, Javanmardi N, Bernard V, Leroy Q, Cappo J, Rio Frio T, Pierron G, Lapouble E, Combaret V, Speleman F, de Wilde B, Djos A, Ora I, Hedborg F, Träger C, Holmqvist BM, Abrahamsson J, Peuchmaur M, Michon J, Janoueix-Lerosey I, Kogner P, Delattre O, Martinsson T. Schleiermacher G, et al. Among authors: trager c. J Clin Oncol. 2014 Sep 1;32(25):2727-34. doi: 10.1200/JCO.2013.54.0674. Epub 2014 Jul 28. J Clin Oncol. 2014. PMID: 25071110
KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine.
Milligan CJ, Li M, Gazina EV, Heron SE, Nair U, Trager C, Reid CA, Venkat A, Younkin DP, Dlugos DJ, Petrovski S, Goldstein DB, Dibbens LM, Scheffer IE, Berkovic SF, Petrou S. Milligan CJ, et al. Among authors: trager c. Ann Neurol. 2014 Apr;75(4):581-90. doi: 10.1002/ana.24128. Epub 2014 Apr 14. Ann Neurol. 2014. PMID: 24591078 Free PMC article.
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