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Drug discovery: new models for industry-academic partnerships.
Tralau-Stewart CJ, Wyatt CA, Kleyn DE, Ayad A. Tralau-Stewart CJ, et al. Drug Discov Today. 2009 Jan;14(1-2):95-101. doi: 10.1016/j.drudis.2008.10.003. Epub 2008 Nov 21. Drug Discov Today. 2009. PMID: 18992364 Review.
UK academic drug discovery.
Tralau-Stewart C, Low CM, Marlin N. Tralau-Stewart C, et al. Nat Rev Drug Discov. 2014 Jan;13(1):15-6. doi: 10.1038/nrd4200. Nat Rev Drug Discov. 2014. PMID: 24378794 No abstract available.
GSK256066, an exceptionally high-affinity and selective inhibitor of phosphodiesterase 4 suitable for administration by inhalation: in vitro, kinetic, and in vivo characterization.
Tralau-Stewart CJ, Williamson RA, Nials AT, Gascoigne M, Dawson J, Hart GJ, Angell AD, Solanke YE, Lucas FS, Wiseman J, Ward P, Ranshaw LE, Knowles RG. Tralau-Stewart CJ, et al. J Pharmacol Exp Ther. 2011 Apr;337(1):145-54. doi: 10.1124/jpet.110.173690. Epub 2011 Jan 4. J Pharmacol Exp Ther. 2011. PMID: 21205923
Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors.
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G. Tornatore L, et al. Cancer Cell. 2014 Oct 13;26(4):495-508. doi: 10.1016/j.ccr.2014.07.027. Cancer Cell. 2014. PMID: 25314077 Free PMC article.
Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors.
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D'Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA, Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G. Tornatore L, et al. Cancer Cell. 2014 Dec 8;26(6):938. doi: 10.1016/j.ccell.2014.11.021. Epub 2014 Dec 8. Cancer Cell. 2014. PMID: 28898681 Free PMC article. No abstract available.
Novel glucocorticoid antedrugs possessing a 17beta-(gamma-lactone) ring.
Procopiou PA, Biggadike K, English AF, Farrell RM, Hagger GN, Hancock AP, Haase MV, Irving WR, Sareen M, Snowden MA, Solanke YE, Tralau-Stewart CJ, Walton SE, Wood JA. Procopiou PA, et al. Among authors: tralau stewart cj. J Med Chem. 2001 Feb 15;44(4):602-12. doi: 10.1021/jm001035c. J Med Chem. 2001. PMID: 11170650