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Tranexamic Acid in Thoracic and Lumbar Fusions and Perioperative Blood Loss.
Wanderman N, Robinson W, Carlson B, Bydon M, Currier B, Huddleston P, Nassr A, Freedman B. Wanderman N, et al. Clin Spine Surg. 2019 Dec;32(10):E462-E468. doi: 10.1097/BSD.0000000000000851. Clin Spine Surg. 2019. PMID: 31169616
OBJECTIVE: The objective of this study was to examine the impact of tranexamic acid (TXA) on total perioperative wound output following thoracic and lumbar spinal fusions. ...However, with surgeries involving fusions >5 levels, TXA may increa …
OBJECTIVE: The objective of this study was to examine the impact of tranexamic acid (TXA) on total perioperative wound …
Intravenous and Oral Tranexamic Acid Are Equivalent at Reducing Blood Loss in Thoracolumbar Spinal Fusion: A Prospective Randomized Trial.
Yu CC, Kadri O, Kadado A, Buraimoh M, Pawloski J, Bartol S, Graziano G. Yu CC, et al. Spine (Phila Pa 1976). 2019 Jun 1;44(11):755-761. doi: 10.1097/BRS.0000000000002954. Spine (Phila Pa 1976). 2019. PMID: 30540715 Clinical Trial.
OBJECTIVE: To compare perioperative blood loss in patients undergoing elective posterior thoracolumbar fusion who were treated with intravenous (IV) versus oral (PO) tranexamic acid (TXA). ...CONCLUSION: Patients treated wit …
OBJECTIVE: To compare perioperative blood loss in patients undergoing elective posterior thoracolumbar fusion
Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis: A randomized trial.
Shi H, Ou Y, Jiang D, Quan Z, Zhao Z, Zhu Y. Shi H, et al. Medicine (Baltimore). 2017 Jan;96(1):e5718. doi: 10.1097/MD.0000000000005718. Medicine (Baltimore). 2017. PMID: 28072709 Free PMC article. Clinical Trial.
This study aimed to evaluate the effect and safety of TA in reducing perioperative blood loss in posterior lumbar surgery for stenosis or spondylolisthesis. ...CONCLUSION: TA significantly reduced the perioperative blood
This study aimed to evaluate the effect and safety of TA in reducing perioperative blood loss in posterior lumba …
Tranexamic Acid reduces perioperative blood loss in adult patients having spinal fusion surgery.
Wong J, El Beheiry H, Rampersaud YR, Lewis S, Ahn H, De Silva Y, Abrishami A, Baig N, McBroom RJ, Chung F. Wong J, et al. Anesth Analg. 2008 Nov;107(5):1479-86. doi: 10.1213/ane.0b013e3181831e44. Anesth Analg. 2008. PMID: 18931202 Clinical Trial.
The objective of this randomized, prospective, double-blind, multicenter study was to evaluate the efficacy of tranexamic acid (TXA) in reducing perioperative blood loss and transfusion in adult patients having elective post …
The objective of this randomized, prospective, double-blind, multicenter study was to evaluate the efficacy of tranexamic acid
Intraoperative tranexamic acid use in major spine surgery in adults: a multicentre, randomized, placebo-controlled trial.
Colomina MJ, Koo M, Basora M, Pizones J, Mora L, Bagó J. Colomina MJ, et al. Br J Anaesth. 2017 Mar 1;118(3):380-390. doi: 10.1093/bja/aew434. Br J Anaesth. 2017. PMID: 28203735 Free article. Clinical Trial.
This study was designed to investigate the hypothesis that TXA reduces perioperative blood loss and transfusion requirements in patients undergoing major spine procedures. ...The incidence of adverse events was similar in the two groups. …
This study was designed to investigate the hypothesis that TXA reduces perioperative blood loss and transfusion …
Intravenous Administration of Tranexamic Acid Significantly Reduces Visible and Hidden Blood Loss Compared with Its Topical Administration for Double-Segment Posterior Lumbar Interbody Fusion: A Single-Center, Placebo-Controlled, Randomized Trial.
Mu X, Wei J, Wang C, Ou Y, Yin D, Liang B, Qiu D, Li Z. Mu X, et al. World Neurosurg. 2019 Feb;122:e821-e827. doi: 10.1016/j.wneu.2018.10.154. Epub 2018 Nov 2. World Neurosurg. 2019. PMID: 30391759 Clinical Trial.
OBJECTIVE: Tranexamic acid (TXA) significantly reduces the visible and hidden blood loss associated with joint replacement. ...SPSS, version 17.0, was used to analyze the patient data, their blood biochemical indices, blood
OBJECTIVE: Tranexamic acid (TXA) significantly reduces the visible and hidden blood loss associated with …
The efficacy and safety of tranexamic acid in reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis: A retrospective observational study.
Xue P, Yang J, Xu X, Liu T, Huang Y, Qiao F, Huang X. Xue P, et al. Medicine (Baltimore). 2018 Dec;97(50):e13643. doi: 10.1097/MD.0000000000013643. Medicine (Baltimore). 2018. PMID: 30558058 Free PMC article.
OBJECTIVE: To investigate the effectiveness and safety of intravenous tranexamic acid for reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis (TSS). ...The patients were divided into …
OBJECTIVE: To investigate the effectiveness and safety of intravenous tranexamic acid for reducing perioperative
The Perioperative Efficacy and Safety of Antifibrinolytics in Adult Spinal Fusion Surgery: A Systematic Review and Meta-analysis.
Lu VM, Ho YT, Nambiar M, Mobbs RJ, Phan K. Lu VM, et al. Spine (Phila Pa 1976). 2018 Aug;43(16):E949-E958. doi: 10.1097/BRS.0000000000002580. Spine (Phila Pa 1976). 2018. PMID: 30063223 Review.
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: Compare outcomes of adult patients undergoing spinal fusion surgery who receive and do not receive perioperative antifibrinolytics to reduce operative blood
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: Compare outcomes of adult patients undergoing spinal f
Antifibrinolytics reduce blood loss in adult spinal deformity surgery: a prospective, randomized controlled trial.
Peters A, Verma K, Slobodyanyuk K, Cheriyan T, Hoelscher C, Schwab F, Lonner B, Huncke T, Lafage V, Errico T. Peters A, et al. Spine (Phila Pa 1976). 2015 Apr 15;40(8):E443-9. doi: 10.1097/BRS.0000000000000799. Spine (Phila Pa 1976). 2015. PMID: 25868100 Clinical Trial.
OBJECTIVE: The purpose of this study was to provide high-quality evidence regarding the comparative efficacies of TXA, EACA, and placebo in reducing blood loss and transfusion requirements in patients undergoing posterior spinal fusion
OBJECTIVE: The purpose of this study was to provide high-quality evidence regarding the comparative efficacies of TXA, EACA, and placebo in …
Effectiveness and Safety of Batroxobin, Tranexamic Acid and a Combination in Reduction of Blood Loss in Lumbar Spinal Fusion Surgery.
Nagabhushan RM, Shetty AP, Dumpa SR, Subramanian B, Kanna RM, Shanmuganathan R. Nagabhushan RM, et al. Spine (Phila Pa 1976). 2018 Mar 1;43(5):E267-E273. doi: 10.1097/BRS.0000000000002315. Spine (Phila Pa 1976). 2018. PMID: 28678111 Clinical Trial.
OBJECTIVE: To evaluate and compare the efficacy and safety of batroxobin (botropase), tranexamic acid (TXA), and their combination in reduction of perioperative blood loss in lumbar spine single level fusion surgeries. ...CONCLUSIO …
OBJECTIVE: To evaluate and compare the efficacy and safety of batroxobin (botropase), tranexamic acid (TXA), and their combina …
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