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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 2
1981 2
1982 1
1983 1
1984 2
1985 3
1986 8
1987 5
1988 17
1989 22
1990 34
1991 46
1992 69
1993 104
1994 125
1995 96
1996 152
1997 158
1998 163
1999 179
2000 163
2001 189
2002 228
2003 268
2004 288
2005 276
2006 305
2007 350
2008 344
2009 347
2010 515
2011 556
2012 627
2013 688
2014 792
2015 862
2016 981
2017 1057
2018 1047
2019 1173
2020 1450
2021 1784
2022 897
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Search Results

14,546 results
Results by year
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Page 1
Female Sex and Alzheimer's Risk: The Menopause Connection.
Scheyer O, Rahman A, Hristov H, Berkowitz C, Isaacson RS, Diaz Brinton R, Mosconi L. Scheyer O, et al. J Prev Alzheimers Dis. 2018;5(4):225-230. doi: 10.14283/jpad.2018.34. J Prev Alzheimers Dis. 2018. PMID: 30298180 Free PMC article. Review.
Along with advanced age and apolipoprotein E (APOE)-4 genotype, female sex is a major risk factor for developing late-onset Alzheimer's disease (AD). Considering that AD pathology begins decades prior to clinical symptoms, the higher risk in women cannot simp …
Along with advanced age and apolipoprotein E (APOE)-4 genotype, female sex is a major risk factor for developing late-onset Alzheimer
Photobiomodulation for Alzheimer's Disease: Translating Basic Research to Clinical Application.
Enengl J, Hamblin MR, Dungel P. Enengl J, et al. J Alzheimers Dis. 2020;75(4):1073-1082. doi: 10.3233/JAD-191210. J Alzheimers Dis. 2020. PMID: 32390621 Free PMC article. Review.
This review covers the literature on photobiomodulation therapy as a novel approach to prevent and treat Alzheimer's disease, aiming to bridge that gap by gathering together the terms and technical specifications into a single concise suggestion for a treatme …
This review covers the literature on photobiomodulation therapy as a novel approach to prevent and treat Alzheimer's diseas
Translating the biology of aging into novel therapeutics for Alzheimer disease.
Hara Y, McKeehan N, Fillit HM. Hara Y, et al. Neurology. 2019 Jan 8;92(2):84-93. doi: 10.1212/WNL.0000000000006745. Epub 2018 Dec 7. Neurology. 2019. PMID: 30530798 Free PMC article. Review.
Aging is the leading risk factor for most chronic illnesses of old age, including Alzheimer disease (AD), a progressive neurodegenerative disease with currently no therapies that prevent, slow, or halt disease progression. ...
Aging is the leading risk factor for most chronic illnesses of old age, including Alzheimer disease (AD), a progressive neurod …
A current view on Tau protein phosphorylation in Alzheimer's disease.
Wegmann S, Biernat J, Mandelkow E. Wegmann S, et al. Curr Opin Neurobiol. 2021 Aug;69:131-138. doi: 10.1016/j.conb.2021.03.003. Epub 2021 Apr 21. Curr Opin Neurobiol. 2021. PMID: 33892381 Free article. Review.
The functions of the neuronal microtubule-associated protein Tau in the central nervous system are regulated by manifold posttranslational modifications at more than 50 sites. ...Elevated phosphorylation and aggregation of Tau are widely considered pathological hallmarks i …
The functions of the neuronal microtubule-associated protein Tau in the central nervous system are regulated by manifold posttranslat …
Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease.
Wesseling H, Mair W, Kumar M, Schlaffner CN, Tang S, Beerepoot P, Fatou B, Guise AJ, Cheng L, Takeda S, Muntel J, Rotunno MS, Dujardin S, Davies P, Kosik KS, Miller BL, Berretta S, Hedreen JC, Grinberg LT, Seeley WW, Hyman BT, Steen H, Steen JA. Wesseling H, et al. Cell. 2020 Dec 10;183(6):1699-1713.e13. doi: 10.1016/j.cell.2020.10.029. Epub 2020 Nov 13. Cell. 2020. PMID: 33188775 Free PMC article.
To elucidate the role of Tau isoforms and post-translational modification (PTM) stoichiometry in Alzheimer's disease (AD), we generated a high-resolution quantitative proteomics map of 95 PTMs on multiple isoforms of Tau isolated from postmortem human …
To elucidate the role of Tau isoforms and post-translational modification (PTM) stoichiometry in Alzheimer's disease
Proteomic landscape of Alzheimer's Disease: novel insights into pathogenesis and biomarker discovery.
Bai B, Vanderwall D, Li Y, Wang X, Poudel S, Wang H, Dey KK, Chen PC, Yang K, Peng J. Bai B, et al. Mol Neurodegener. 2021 Aug 12;16(1):55. doi: 10.1186/s13024-021-00474-z. Mol Neurodegener. 2021. PMID: 34384464 Free PMC article. Review.
Mass spectrometry-based proteomics empowers deep profiling of proteome and protein posttranslational modifications (PTMs) in Alzheimer's disease (AD). ...In particular, tau PTMs are correlated with disease stages and indicate the heterogeneity o …
Mass spectrometry-based proteomics empowers deep profiling of proteome and protein posttranslational modifications (PTMs) in Alzhe
Multimodal Neuroimaging in Alzheimer's Disease: Early Diagnosis, Physiopathological Mechanisms, and Impact of Lifestyle.
Chételat G. Chételat G. J Alzheimers Dis. 2018;64(s1):S199-S211. doi: 10.3233/JAD-179920. J Alzheimers Dis. 2018. PMID: 29504542 Free PMC article. Review.
Over the last ten years, we have conducted research in Alzheimer's disease (AD) using multimodal neuroimaging techniques to improve diagnosis, further our understanding of the pathological mechanisms underlying the disease, and support the development …
Over the last ten years, we have conducted research in Alzheimer's disease (AD) using multimodal neuroimaging technique …
Acetylation changes tau interactome to degrade tau in Alzheimer's disease animal and organoid models.
Choi H, Kim HJ, Yang J, Chae S, Lee W, Chung S, Kim J, Choi H, Song H, Lee CK, Jun JH, Lee YJ, Lee K, Kim S, Sim HR, Choi YI, Ryu KH, Park JC, Lee D, Han SH, Hwang D, Kyung J, Mook-Jung I. Choi H, et al. Aging Cell. 2020 Jan;19(1):e13081. doi: 10.1111/acel.13081. Epub 2019 Nov 25. Aging Cell. 2020. PMID: 31763743 Free PMC article.
Alzheimer's disease (AD) is an age-related neurodegenerative disease. ...
Alzheimer's disease (AD) is an age-related neurodegenerative disease. ...
Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies.
Šimić G, Babić Leko M, Wray S, Harrington C, Delalle I, Jovanov-Milošević N, Bažadona D, Buée L, de Silva R, Di Giovanni G, Wischik C, Hof PR. Šimić G, et al. Biomolecules. 2016 Jan 6;6(1):6. doi: 10.3390/biom6010006. Biomolecules. 2016. PMID: 26751493 Free PMC article. Review.
Abnormal deposition of misprocessed and aggregated proteins is a common final pathway of most neurodegenerative diseases, including Alzheimer's disease (AD). AD is characterized by the extraneuronal deposition of the amyloid beta (Abeta) protein in the …
Abnormal deposition of misprocessed and aggregated proteins is a common final pathway of most neurodegenerative diseases, including Alzhe
Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine.
Neuner SM, Heuer SE, Huentelman MJ, O'Connell KMS, Kaczorowski CC. Neuner SM, et al. Neuron. 2019 Feb 6;101(3):399-411.e5. doi: 10.1016/j.neuron.2018.11.040. Epub 2018 Dec 27. Neuron. 2019. PMID: 30595332 Free PMC article.
An individual's genetic makeup plays a large role in determining susceptibility to Alzheimer's disease (AD) but has largely been ignored in preclinical studies. ...Overall, work here both introduces a novel AD mouse population as an innovative and repr …
An individual's genetic makeup plays a large role in determining susceptibility to Alzheimer's disease (AD) but …
14,546 results
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