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Translation inhibitors cause abnormalities in ribosome profiling experiments.
Gerashchenko MV, Gladyshev VN. Gerashchenko MV, et al. Nucleic Acids Res. 2014;42(17):e134. doi: 10.1093/nar/gku671. Epub 2014 Jul 23. Nucleic Acids Res. 2014. PMID: 25056308 Free PMC article.
Ribosome profiling and high-throughput sequencing provide unprecedented opportunities for the analysis of mRNA translation. ...Likewise, we find little support for short upstream reading frames to be involved in widespread protein synthesis regulation
Ribosome profiling and high-throughput sequencing provide unprecedented opportunities for the analysis of mRNA translation
NAT10 Is Involved in Cardiac Remodeling Through ac4C-Mediated Transcriptomic Regulation.
Shi J, Yang C, Zhang J, Zhao K, Li P, Kong C, Wu X, Sun H, Zheng R, Sun W, Chen L, Kong X. Shi J, et al. Circ Res. 2023 Dec 8;133(12):989-1002. doi: 10.1161/CIRCRESAHA.122.322244. Epub 2023 Nov 13. Circ Res. 2023. PMID: 37955115 Free article.
Next-generation sequencing revealed ac4C changes in both mice and humans with cardiac hypertrophy were associated with changes in global mRNA abundance, stability, and translation efficiency. Mechanistically, NAT10 could enhance the stability and translation efficie …
Next-generation sequencing revealed ac4C changes in both mice and humans with cardiac hypertrophy were associated with changes in global mRN …