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A conformation-specific ON-switch for controlling CAR T cells with an orally available drug.
Zajc CU, Dobersberger M, Schaffner I, Mlynek G, Pühringer D, Salzer B, Djinović-Carugo K, Steinberger P, De Sousa Linhares A, Yang NJ, Obinger C, Holter W, Traxlmayr MW, Lehner M. Zajc CU, et al. Among authors: traxlmayr mw. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):14926-14935. doi: 10.1073/pnas.1911154117. Epub 2020 Jun 17. Proc Natl Acad Sci U S A. 2020. PMID: 32554495 Free PMC article.
Engineered IgG1-Fc--one fragment to bind them all.
Lobner E, Traxlmayr MW, Obinger C, Hasenhindl C. Lobner E, et al. Among authors: traxlmayr mw. Immunol Rev. 2016 Mar;270(1):113-31. doi: 10.1111/imr.12385. Immunol Rev. 2016. PMID: 26864108 Free PMC article. Review.
Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies.
Lobner E, Humm AS, Göritzer K, Mlynek G, Puchinger MG, Hasenhindl C, Rüker F, Traxlmayr MW, Djinović-Carugo K, Obinger C. Lobner E, et al. Among authors: traxlmayr mw. Structure. 2017 Jun 6;25(6):878-889.e5. doi: 10.1016/j.str.2017.04.014. Epub 2017 May 18. Structure. 2017. PMID: 28528777 Free article.
31 results