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Targeting cytokines as a treatment for patients with sepsis: A lost cause or a strategy still worthy of pursuit?
Brown KA, Brown GA, Lewis SM, Beale R, Treacher DF. Brown KA, et al. Among authors: treacher df. Int Immunopharmacol. 2016 Jul;36:291-299. doi: 10.1016/j.intimp.2016.04.041. Epub 2016 May 19. Int Immunopharmacol. 2016. PMID: 27208433 Review.
Expression of CD11c and EMR2 on neutrophils: potential diagnostic biomarkers for sepsis and systemic inflammation.
Lewis SM, Treacher DF, Edgeworth J, Mahalingam G, Brown CS, Mare TA, Stacey M, Beale R, Brown KA. Lewis SM, et al. Among authors: treacher df. Clin Exp Immunol. 2015 Nov;182(2):184-94. doi: 10.1111/cei.12679. Epub 2015 Sep 22. Clin Exp Immunol. 2015. PMID: 26153037 Free PMC article.
The diagnostic and prognostic significance of monitoring blood levels of immature neutrophils in patients with systemic inflammation.
Mare TA, Treacher DF, Shankar-Hari M, Beale R, Lewis SM, Chambers DJ, Brown KA. Mare TA, et al. Among authors: treacher df. Crit Care. 2015 Feb 25;19(1):57. doi: 10.1186/s13054-015-0778-z. Crit Care. 2015. PMID: 25887201 Free PMC article.
Quantification of microcirculatory blood flow: a sensitive and clinically relevant prognostic marker in murine models of sepsis.
Sand CA, Starr A, Wilder CD, Rudyk O, Spina D, Thiemermann C, Treacher DF, Nandi M. Sand CA, et al. Among authors: treacher df. J Appl Physiol (1985). 2015 Feb 1;118(3):344-54. doi: 10.1152/japplphysiol.00793.2014. Epub 2014 Dec 4. J Appl Physiol (1985). 2015. PMID: 25477352 Free PMC article.
Depletion of blood neutrophils from patients with sepsis: treatment for the future?
Lewis SM, Khan N, Beale R, Treacher DF, Brown KA. Lewis SM, et al. Among authors: treacher df. Int Immunopharmacol. 2013 Dec;17(4):1226-32. doi: 10.1016/j.intimp.2013.10.002. Epub 2013 Oct 18. Int Immunopharmacol. 2013. PMID: 24144812 Review.
Metabolic effects of intensive insulin therapy in critically ill patients.
Whyte MB, Jackson NC, Shojaee-Moradie F, Treacher DF, Beale RJ, Jones RH, Umpleby AM. Whyte MB, et al. Among authors: treacher df. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E697-705. doi: 10.1152/ajpendo.00407.2009. Epub 2009 Dec 22. Am J Physiol Endocrinol Metab. 2010. PMID: 20028969 Free article. Clinical Trial.
Plasma from patients with sepsis up-regulates the expression of CD49d and CD64 on blood neutrophils.
Lewis SM, Treacher DF, Bergmeier L, Brain SD, Chambers DJ, Pearson JD, Brown KA. Lewis SM, et al. Among authors: treacher df. Am J Respir Cell Mol Biol. 2009 Jun;40(6):724-32. doi: 10.1165/rcmb.2008-0252OC. Epub 2008 Nov 14. Am J Respir Cell Mol Biol. 2009. PMID: 19011162
Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function.
Yona S, Lin HH, Dri P, Davies JQ, Hayhoe RP, Lewis SM, Heinsbroek SE, Brown KA, Perretti M, Hamann J, Treacher DF, Gordon S, Stacey M. Yona S, et al. Among authors: treacher df. FASEB J. 2008 Mar;22(3):741-51. doi: 10.1096/fj.07-9435com. Epub 2007 Oct 10. FASEB J. 2008. PMID: 17928360
Neutrophils as potential therapeutic targets in sepsis.
Brown KA, Treacher DF. Brown KA, et al. Among authors: treacher df. Discov Med. 2006 Jun;6(33):118-22. Discov Med. 2006. PMID: 17234146 Free article.
Neutrophils in development of multiple organ failure in sepsis.
Brown KA, Brain SD, Pearson JD, Edgeworth JD, Lewis SM, Treacher DF. Brown KA, et al. Among authors: treacher df. Lancet. 2006 Jul 8;368(9530):157-69. doi: 10.1016/S0140-6736(06)69005-3. Lancet. 2006. PMID: 16829300 Review.
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