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Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet.
Penke M, Larsen PS, Schuster S, Dall M, Jensen BA, Gorski T, Meusel A, Richter S, Vienberg SG, Treebak JT, Kiess W, Garten A. Penke M, et al. Among authors: treebak jt. Mol Cell Endocrinol. 2015 Sep 5;412:65-72. doi: 10.1016/j.mce.2015.05.028. Epub 2015 May 29. Mol Cell Endocrinol. 2015. PMID: 26033245
Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain.
Jensen BA, Nielsen TS, Fritzen AM, Holm JB, Fjære E, Serup AK, Borkowski K, Risis S, Pærregaard SI, Søgaard I, Poupeau A, Poulsen M, Ma T, Sina C, Kiens B, Madsen L, Kristiansen K, Treebak JT. Jensen BA, et al. Among authors: treebak jt. Metabolism. 2016 Dec;65(12):1706-1719. doi: 10.1016/j.metabol.2016.09.002. Epub 2016 Sep 12. Metabolism. 2016. PMID: 27832859 Free article.
Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle.
Agerholm M, Dall M, Jensen BAH, Prats C, Madsen S, Basse AL, Graae AS, Risis S, Goldenbaum J, Quistorff B, Larsen S, Vienberg SG, Treebak JT. Agerholm M, et al. Among authors: treebak jt. Am J Physiol Endocrinol Metab. 2018 Apr 1;314(4):E377-E395. doi: 10.1152/ajpendo.00213.2017. Epub 2017 Dec 5. Am J Physiol Endocrinol Metab. 2018. PMID: 29208611 Free article.
Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin-resistant men.
Dollerup OL, Chubanava S, Agerholm M, Søndergård SD, Altıntaş A, Møller AB, Høyer KF, Ringgaard S, Stødkilde-Jørgensen H, Lavery GG, Barrès R, Larsen S, Prats C, Jessen N, Treebak JT. Dollerup OL, et al. Among authors: treebak jt. J Physiol. 2020 Feb;598(4):731-754. doi: 10.1113/JP278752. Epub 2019 Dec 26. J Physiol. 2020. PMID: 31710095 Free article. Clinical Trial.
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism.
Jensen BAH, Holm JB, Larsen IS, von Burg N, Derer S, Sonne SB, Pærregaard SI, Damgaard MV, Indrelid SA, Rivollier A, Agrinier AL, Sulek K, Arnoldussen YJ, Fjære E, Marette A, Angell IL, Rudi K, Treebak JT, Madsen L, Åkesson CP, Agace W, Sina C, Kleiveland CR, Kristiansen K, Lea TE. Jensen BAH, et al. Among authors: treebak jt. Nat Commun. 2021 Feb 17;12(1):1093. doi: 10.1038/s41467-021-21408-9. Nat Commun. 2021. PMID: 33597537 Free PMC article.
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity.
Basse AL, Agerholm M, Farup J, Dalbram E, Nielsen J, Ørtenblad N, Altıntaş A, Ehrlich AM, Krag T, Bruzzone S, Dall M, de Guia RM, Jensen JB, Møller AB, Karlsen A, Kjær M, Barrès R, Vissing J, Larsen S, Jessen N, Treebak JT. Basse AL, et al. Among authors: treebak jt. Mol Metab. 2021 Nov;53:101271. doi: 10.1016/j.molmet.2021.101271. Epub 2021 Jun 11. Mol Metab. 2021. PMID: 34119711 Free PMC article.
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