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The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.
Belda H, Bradley D, Christodoulou E, Nofal SD, Broncel M, Jones D, Davies H, Bertran MT, Purkiss AG, Ogrodowicz RW, Joshi D, O'Reilly N, Walport L, Powell A, House D, Kjaer S, Claessens A, Landry CR, Treeck M. Belda H, et al. Among authors: treeck m. Nat Microbiol. 2025 Jun;10(6):1463-1483. doi: 10.1038/s41564-025-02017-4. Epub 2025 May 19. Nat Microbiol. 2025. PMID: 40389650 Free PMC article.
Gliding motility of Plasmodium merozoites.
Yahata K, Hart MN, Davies H, Asada M, Wassmer SC, Templeton TJ, Treeck M, Moon RW, Kaneko O. Yahata K, et al. Among authors: treeck m. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2114442118. doi: 10.1073/pnas.2114442118. Proc Natl Acad Sci U S A. 2021. PMID: 34819379 Free PMC article.
The Plasmodium Lactate/H+ Transporter PfFNT Is Essential and Druggable In Vivo.
Davies H, Bergmann B, Walloch P, Nerlich C, Hansen C, Wittlin S, Spielmann T, Treeck M, Beitz E. Davies H, et al. Among authors: treeck m. Antimicrob Agents Chemother. 2023 Aug 17;67(8):e0035623. doi: 10.1128/aac.00356-23. Epub 2023 Jul 10. Antimicrob Agents Chemother. 2023. PMID: 37428074 Free PMC article.
55 results