Trifunovic A - Search Results

1

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.

Falkenberg M, Gaspari M, Rantanen A, Trifunovic A, Larsson NG, Gustafsson CM. Falkenberg M, et al. Among authors: trifunovic a. Nat Genet. 2002 Jul;31(3):289-94. doi: 10.1038/ng909. Epub 2002 Jun 17. Nat Genet. 2002. PMID: 12068295

2

Premature ageing in mice expressing defective mitochondrial DNA polymerase.

Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, Bruder CE, Bohlooly-Y M, Gidlöf S, Oldfors A, Wibom R, Törnell J, Jacobs HT, Larsson NG. Trifunovic A, et al. Nature. 2004 May 27;429(6990):417-23. doi: 10.1038/nature02517. Nature. 2004. PMID: 15164064

3

Tissue-specific knockout model for study of mitochondrial DNA mutation disorders.

Trifunovic A, Larsson NG. Trifunovic A, et al. Methods Enzymol. 2002;353:409-21. doi: 10.1016/s0076-6879(02)53065-2. Methods Enzymol. 2002. PMID: 12078514 No abstract available.

4

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.

Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, Khvorostov I, Spelbrink JN, Wibom R, Jacobs HT, Larsson NG. Trifunovic A, et al. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17993-8. doi: 10.1073/pnas.0508886102. Epub 2005 Dec 6. Proc Natl Acad Sci U S A. 2005. PMID: 16332961 Free PMC article.

5

Somatic mtDNA mutations cause progressive hearing loss in the mouse.

Niu X, Trifunovic A, Larsson NG, Canlon B. Niu X, et al. Among authors: trifunovic a. Exp Cell Res. 2007 Nov 1;313(18):3924-34. doi: 10.1016/j.yexcr.2007.05.029. Epub 2007 Jun 29. Exp Cell Res. 2007. PMID: 17662273

6

Strong purifying selection in transmission of mammalian mitochondrial DNA.

Stewart JB, Freyer C, Elson JL, Wredenberg A, Cansu Z, Trifunovic A, Larsson NG. Stewart JB, et al. Among authors: trifunovic a. PLoS Biol. 2008 Jan;6(1):e10. doi: 10.1371/journal.pbio.0060010. PLoS Biol. 2008. PMID: 18232733 Free PMC article.

7

Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice.

Edgar D, Shabalina I, Camara Y, Wredenberg A, Calvaruso MA, Nijtmans L, Nedergaard J, Cannon B, Larsson NG, Trifunovic A. Edgar D, et al. Among authors: trifunovic a. Cell Metab. 2009 Aug;10(2):131-8. doi: 10.1016/j.cmet.2009.06.010. Cell Metab. 2009. PMID: 19656491 Free article.

8

Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons.

Ekstrand MI, Terzioglu M, Galter D, Zhu S, Hofstetter C, Lindqvist E, Thams S, Bergstrand A, Hansson FS, Trifunovic A, Hoffer B, Cullheim S, Mohammed AH, Olson L, Larsson NG. Ekstrand MI, et al. Among authors: trifunovic a. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1325-30. doi: 10.1073/pnas.0605208103. Epub 2007 Jan 16. Proc Natl Acad Sci U S A. 2007. PMID: 17227870 Free PMC article.

9

Point mutations are causing progeroid phenotypes in the mtDNA mutator mouse.

Edgar D, Larsson NG, Trifunovic A. Edgar D, et al. Among authors: trifunovic a. Cell Metab. 2010 Jan;11(1):1. doi: 10.1016/j.cmet.2009.12.001. Cell Metab. 2010. PMID: 20005181 Free article. No abstract available.

10

High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio.

Ross JM, Öberg J, Brené S, Coppotelli G, Terzioglu M, Pernold K, Goiny M, Sitnikov R, Kehr J, Trifunovic A, Larsson NG, Hoffer BJ, Olson L. Ross JM, et al. Among authors: trifunovic a. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20087-92. doi: 10.1073/pnas.1008189107. Epub 2010 Nov 1. Proc Natl Acad Sci U S A. 2010. PMID: 21041631 Free PMC article.

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