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Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-alpha gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity.
Frittitta L, Youngren JF, Sbraccia P, D'Adamo M, Buongiorno A, Vigneri R, Goldfine ID, Trischitta V. Frittitta L, et al. Among authors: trischitta v. Diabetologia. 1997 Mar;40(3):282-9. doi: 10.1007/s001250050675. Diabetologia. 1997. PMID: 9084965
Membrane glycoprotein PC-1 and insulin resistance.
Goldfine ID, Maddux BA, Youngren JF, Frittitta L, Trischitta V, Dohm GL. Goldfine ID, et al. Among authors: trischitta v. Mol Cell Biochem. 1998 May;182(1-2):177-84. Mol Cell Biochem. 1998. PMID: 9609127 Review.
Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling.
Frittitta L, Spampinato D, Solini A, Nosadini R, Goldfine ID, Vigneri R, Trischitta V. Frittitta L, et al. Among authors: trischitta v. Diabetes. 1998 Jul;47(7):1095-100. doi: 10.2337/diabetes.47.7.1095. Diabetes. 1998. PMID: 9648833
277 results