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Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB.
Hofmann MA, Schiekofer S, Isermann B, Kanitz M, Henkels M, Joswig M, Treusch A, Morcos M, Weiss T, Borcea V, Abdel Khalek AK, Amiral J, Tritschler H, Ritz E, Wahl P, Ziegler R, Bierhaus A, Nawroth PP. Hofmann MA, et al. Diabetologia. 1999 Feb;42(2):222-32. doi: 10.1007/s001250051142. Diabetologia. 1999. PMID: 10064103
Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy.
Reljanovic M, Reichel G, Rett K, Lobisch M, Schuette K, Möller W, Tritschler HJ, Mehnert H. Reljanovic M, et al. Among authors: tritschler hj. Free Radic Res. 1999 Sep;31(3):171-9. doi: 10.1080/10715769900300721. Free Radic Res. 1999. PMID: 10499773 Clinical Trial.
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