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Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway.
Déléris P, Trost M, Topisirovic I, Tanguay PL, Borden KL, Thibault P, Meloche S. Déléris P, et al. Among authors: Trost M. J Biol Chem. 2011 Feb 25;286(8):6470-8. doi: 10.1074/jbc.M110.181529. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177870 Free PMC article.
Subcellular phosphoproteomics.
Trost M, Bridon G, Desjardins M, Thibault P. Trost M, et al. Mass Spectrom Rev. 2010 Nov-Dec;29(6):962-90. doi: 10.1002/mas.20297. Mass Spectrom Rev. 2010. PMID: 20931658 Review.
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, Hofmann K, Alessi DR, Knebel A, Trost M, Muqit MM. Kazlauskaite A, et al. Among authors: Trost M. Biochem J. 2014 May 15;460(1):127-39. doi: 10.1042/BJ20140334. Biochem J. 2014. PMID: 24660806 Free PMC article.
Using phosphoproteomic analysis, we identified a novel ubiquitin phosphopeptide phosphorylated at Ser65 that was enriched 14-fold in HEK (human embryonic kidney)-293 cells overexpressing wild-type PINK1 stimulated with the mitochondrial uncoupling agent CCCP (carbonyl cyanide m-chlorophenylhydrazone), to activate PINK1, compared with cells expressing kinase-inactive PINK1. ...
Using phosphoproteomic analysis, we identified a novel ubiquitin phosphopeptide phosphorylated at Ser65 that was enriched 14-fold in HEK (hu …
Combined enzymatic and data mining approaches for comprehensive phosphoproteome analyses: application to cell signaling events of interferon-gamma-stimulated macrophages.
Marcantonio M, Trost M, Courcelles M, Desjardins M, Thibault P. Marcantonio M, et al. Among authors: Trost M. Mol Cell Proteomics. 2008 Apr;7(4):645-60. doi: 10.1074/mcp.M700383-MCP200. Epub 2007 Nov 14. Mol Cell Proteomics. 2008. PMID: 18006492
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.
Lai YC, Kondapalli C, Lehneck R, Procter JB, Dill BD, Woodroof HI, Gourlay R, Peggie M, Macartney TJ, Corti O, Corvol JC, Campbell DG, Itzen A, Trost M, Muqit MM. Lai YC, et al. Among authors: Trost M. Version 2. EMBO J. 2015 Nov 12;34(22):2840-61. doi: 10.15252/embj.201591593. Epub 2015 Oct 15. EMBO J. 2015. PMID: 26471730 Free PMC article.
Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP.
Topisirovic I, Siddiqui N, Lapointe VL, Trost M, Thibault P, Bangeranye C, Piñol-Roma S, Borden KL. Topisirovic I, et al. Among authors: Trost M. EMBO J. 2009 Apr 22;28(8):1087-98. doi: 10.1038/emboj.2009.53. Epub 2009 Mar 5. EMBO J. 2009. PMID: 19262567 Free PMC article.
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