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Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax.
Zhang Z, Lapolla SM, Annis MG, Truscott M, Roberts GJ, Miao Y, Shao Y, Tan C, Peng J, Johnson AE, Zhang XC, Andrews DW, Lin J. Zhang Z, et al. Among authors: truscott m. J Biol Chem. 2004 Oct 15;279(42):43920-8. doi: 10.1074/jbc.M406412200. Epub 2004 Aug 9. J Biol Chem. 2004. PMID: 15302859 Free PMC article.
An intronic microRNA links Rb/E2F and EGFR signaling.
Truscott M, Islam AB, Lightfoot J, López-Bigas N, Frolov MV. Truscott M, et al. PLoS Genet. 2014 Jul 24;10(7):e1004493. doi: 10.1371/journal.pgen.1004493. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25058496 Free PMC article.
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