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New insights into the role of podocytes in proteinuria.
Patrakka J, Tryggvason K. Patrakka J, et al. Among authors: tryggvason k. Nat Rev Nephrol. 2009 Aug;5(8):463-8. doi: 10.1038/nrneph.2009.108. Epub 2009 Jul 7. Nat Rev Nephrol. 2009. PMID: 19581907 Review.
A reverse genetic screen in the zebrafish identifies crb2b as a regulator of the glomerular filtration barrier.
Ebarasi L, He L, Hultenby K, Takemoto M, Betsholtz C, Tryggvason K, Majumdar A. Ebarasi L, et al. Among authors: tryggvason k. Dev Biol. 2009 Oct 1;334(1):1-9. doi: 10.1016/j.ydbio.2009.04.017. Epub 2009 Apr 23. Dev Biol. 2009. PMID: 19393641
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511.
Rodin S, Domogatskaya A, Ström S, Hansson EM, Chien KR, Inzunza J, Hovatta O, Tryggvason K. Rodin S, et al. Among authors: tryggvason k. Nat Biotechnol. 2010 Jun;28(6):611-5. doi: 10.1038/nbt.1620. Epub 2010 May 30. Nat Biotechnol. 2010. PMID: 20512123
Glomerular transcriptome changes associated with lipopolysaccharide-induced proteinuria.
Sun Y, He L, Takemoto M, Patrakka J, Pikkarainen T, Genové G, Norlin J, Truvé K, Tryggvason K, Betsholtz C. Sun Y, et al. Among authors: tryggvason k. Am J Nephrol. 2009;29(6):558-70. doi: 10.1159/000191469. Epub 2009 Jan 9. Am J Nephrol. 2009. PMID: 19136817
Rhophilin-1 is a key regulator of the podocyte cytoskeleton and is essential for glomerular filtration.
Lal MA, Andersson AC, Katayama K, Xiao Z, Nukui M, Hultenby K, Wernerson A, Tryggvason K. Lal MA, et al. Among authors: tryggvason k. J Am Soc Nephrol. 2015 Mar;26(3):647-62. doi: 10.1681/ASN.2013111195. Epub 2014 Jul 28. J Am Soc Nephrol. 2015. PMID: 25071083 Free PMC article.
Expression of novel podocyte-associated proteins sult1b1 and ankrd25.
Xu X, Patrakka J, Sistani L, Uhlen M, Jalanko H, Betsholtz C, Tryggvason K. Xu X, et al. Among authors: tryggvason k. Nephron Exp Nephrol. 2011;117(2):e39-46. doi: 10.1159/000320049. Epub 2010 Aug 18. Nephron Exp Nephrol. 2011. PMID: 20720434
Molecular make-up of the glomerular filtration barrier.
Patrakka J, Tryggvason K. Patrakka J, et al. Among authors: tryggvason k. Biochem Biophys Res Commun. 2010 May 21;396(1):164-9. doi: 10.1016/j.bbrc.2010.04.069. Biochem Biophys Res Commun. 2010. PMID: 20494132 Review.
Dendrin expression in glomerulogenesis and in human minimal change nephrotic syndrome.
Dunér F, Patrakka J, Xiao Z, Larsson J, Vlamis-Gardikas A, Pettersson E, Tryggvason K, Hultenby K, Wernerson A. Dunér F, et al. Among authors: tryggvason k. Nephrol Dial Transplant. 2008 Aug;23(8):2504-11. doi: 10.1093/ndt/gfn100. Epub 2008 Mar 20. Nephrol Dial Transplant. 2008. PMID: 18356187
Laminin isoforms of lymph nodes and predominant role of alpha5-laminin(s) in adhesion and migration of blood lymphocytes.
Gorfu G, Virtanen I, Hukkanen M, Lehto VP, Rousselle P, Kenne E, Lindbom L, Kramer R, Tryggvason K, Patarroyo M. Gorfu G, et al. Among authors: tryggvason k. J Leukoc Biol. 2008 Sep;84(3):701-12. doi: 10.1189/jlb.0108048. Epub 2008 Jun 12. J Leukoc Biol. 2008. PMID: 18523231
Sp1 specifically binds to an evolutionarily conserved DNA segment within a region necessary for podocyte-specific expression of nephrin.
Beltcheva O, Hjorleifsdottir EE, Kontusaari S, Tryggvason K. Beltcheva O, et al. Among authors: tryggvason k. Nephron Exp Nephrol. 2010;114(1):e15-22. doi: 10.1159/000245062. Epub 2009 Oct 9. Nephron Exp Nephrol. 2010. PMID: 19816048
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