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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
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1966 3
1967 2
1969 2
1970 3
1971 1
1972 1
1973 3
1974 2
1975 2
1976 2
1977 2
1978 4
1979 4
1980 3
1981 5
1982 2
1983 6
1984 3
1985 3
1986 2
1988 1
1989 2
1990 2
1991 3
1992 1
1994 2
1995 1
1996 1
1997 3
1998 3
1999 6
2000 2
2002 2
2003 5
2004 1
2005 5
2006 6
2007 9
2008 7
2009 6
2010 5
2011 3
2012 7
2013 4
2014 9
2015 10
2016 14
2017 7
2018 13
2019 18
2020 15
2021 12
2022 14
2023 0
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238 results
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Page 1
Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.
Schirmer M, Smeekens SP, Vlamakis H, Jaeger M, Oosting M, Franzosa EA, Ter Horst R, Jansen T, Jacobs L, Bonder MJ, Kurilshikov A, Fu J, Joosten LAB, Zhernakova A, Huttenhower C, Wijmenga C, Netea MG, Xavier RJ. Schirmer M, et al. Cell. 2016 Nov 3;167(4):1125-1136.e8. doi: 10.1016/j.cell.2016.10.020. Cell. 2016. PMID: 27814509 Free PMC article.
Validation of two predicted host-microbial interactions reveal that TNFalpha and IFNgamma production are associated with specific microbial metabolic pathways: palmitoleic acid metabolism and tryptophan degradation to tryptophol. Besides providing a resource of predicted m …
Validation of two predicted host-microbial interactions reveal that TNFalpha and IFNgamma production are associated with specific microbial …
AhR/IL-22 pathway as new target for the treatment of post-infectious irritable bowel syndrome symptoms.
Meynier M, Baudu E, Rolhion N, Defaye M, Straube M, Daugey V, Modoux M, Wawrzyniak I, Delbac F, Villéger R, Méleine M, Borras Nogues E, Godfraind C, Barnich N, Ardid D, Poirier P, Sokol H, Chatel JM, Langella P, Livrelli V, Bonnet M, Carvalho FA. Meynier M, et al. Gut Microbes. 2022 Jan-Dec;14(1):2022997. doi: 10.1080/19490976.2021.2022997. Gut Microbes. 2022. PMID: 35090380 Free PMC article.
During post-infection period, the indole pathway and AhR activity were decreased due to a reduction of tryptophol production. Treatment with L. lactis(IL-22) restored gut permeability and normalized colonic sensitivity, restored cognitive performances and decreased anxiety …
During post-infection period, the indole pathway and AhR activity were decreased due to a reduction of tryptophol production. Treatme …
Aminotransferase SsAro8 Regulates Tryptophan Metabolism Essential for Filamentous Growth of Sugarcane Smut Fungus Sporisorium scitamineum.
Cui G, Huang C, Bi X, Wang Y, Yin K, Zhu L, Jiang Z, Chen B, Deng YZ. Cui G, et al. Microbiol Spectr. 2022 Aug 31;10(4):e0057022. doi: 10.1128/spectrum.00570-22. Epub 2022 Jul 6. Microbiol Spectr. 2022. PMID: 35862944 Free PMC article.
Our comparative transcriptome analysis showed that the mitogen-activated protein kinase (MAPK) pathway and the AGC kinase Agc1 (orthologous to yeast Rim15), both governing S. scitamineum mating/filamentation, were induced by elevated tryptophol level, supporting a positive …
Our comparative transcriptome analysis showed that the mitogen-activated protein kinase (MAPK) pathway and the AGC kinase Agc1 (orthologous …
The effects of a thermophile metabolite, tryptophol, upon protecting shrimp against white spot syndrome virus.
Zhu F, Jin M. Zhu F, et al. Fish Shellfish Immunol. 2015 Dec;47(2):777-81. doi: 10.1016/j.fsi.2015.10.015. Epub 2015 Oct 19. Fish Shellfish Immunol. 2015. PMID: 26492993

Our results revealed that 50 mg/kg tryptophol has a better protective effect in shrimp than 10 or 100 mg/kg tryptophol. WSSV copies in shrimp were reduced significantly (P < 0.01) when supplemented with 50 mg/kg tryptophol, indicating that virus replicatio

Our results revealed that 50 mg/kg tryptophol has a better protective effect in shrimp than 10 or 100 mg/kg tryptophol. WSSV c …
Metabolism of tryptophol in higher and lower plants.
Laćan G, Magnus V, Simaga S, Iskrić S, Hall PJ. Laćan G, et al. Plant Physiol. 1985 Jul;78(3):447-54. doi: 10.1104/pp.78.3.447. Plant Physiol. 1985. PMID: 16664264 Free PMC article.
Bacteria, thallophytes, and seed plants (107 species), supplied with exogenous indole-3-ethanol (tryptophol), formed one or more of the following metabolites: O-acetyl tryptophol, an unknown tryptophol ester (or a set of structurally closely related esters), …
Bacteria, thallophytes, and seed plants (107 species), supplied with exogenous indole-3-ethanol (tryptophol), formed one or more of t …
Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds.
Palmieri A, Petrini M. Palmieri A, et al. Nat Prod Rep. 2019 Mar 20;36(3):490-530. doi: 10.1039/c8np00032h. Nat Prod Rep. 2019. PMID: 30230504 Review.
Covering: up to 2018 Tryptophol (indole-3-ethanol) is a metabolite produced by plants, bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and various synthetic approaches to the preparation of tryptophol and its derivatives. Synt …
Covering: up to 2018 Tryptophol (indole-3-ethanol) is a metabolite produced by plants, bacteria, fungi and sponges. This review repor …
Suppression of the pathogenicity of Candida albicans by the quorum-sensing molecules farnesol and tryptophol.
Singkum P, Muangkaew W, Suwanmanee S, Pumeesat P, Wongsuk T, Luplertlop N. Singkum P, et al. J Gen Appl Microbiol. 2020 Jan 31;65(6):277-283. doi: 10.2323/jgam.2018.12.002. Epub 2019 Jun 18. J Gen Appl Microbiol. 2020. PMID: 31217414 Free article.
Further, pretreatment of C. albicans with tryptophol or farnesol prior to G. mellonella larval infection significantly enhanced host survival compared with larvae infected with untreated C. albicans. Thus, farnesol and tryptophol may trigger apoptosis of C. albicans …
Further, pretreatment of C. albicans with tryptophol or farnesol prior to G. mellonella larval infection significantly enhanced host …
Tryptophol induces death receptor (DR) 5-mediated apoptosis in U937 cells.
Inagaki S, Morimura S, Tang Y, Akutagawa H, Kida K. Inagaki S, et al. Biosci Biotechnol Biochem. 2007 Aug;71(8):2065-8. doi: 10.1271/bbb.70084. Epub 2007 Aug 7. Biosci Biotechnol Biochem. 2007. PMID: 17690453 Free article.
Tryptophol, however, did not affect human peripheral blood lymphocytes (PBL). ...These results indicate that tryptophol induces apoptosis through DR5 and that the resistance of PBL to tryptophol-induced apoptosis might be due to competition from DcR1....
Tryptophol, however, did not affect human peripheral blood lymphocytes (PBL). ...These results indicate that tryptophol induce
Rapid distribution of tryptophol (3-indole ethanol) to the brain and other tissues.
Cornford EM, Bocash WD, Braun LD, Crane PD, Oldendorf WH, MacInnis AJ. Cornford EM, et al. J Clin Invest. 1979 Jun;63(6):1241-8. doi: 10.1172/JCI109419. J Clin Invest. 1979. PMID: 447842 Free PMC article.
We prepared, purified, and characterized radiolabeled tryptophol for the purpose of defining its tissue distribution in animals. Tryptophol was found to be highly lipophilic, with an octanol:water partition coefficient of 29.8. ...
We prepared, purified, and characterized radiolabeled tryptophol for the purpose of defining its tissue distribution in animals. T
Genotoxicity of tryptophol in a battery of short-term assays on human white blood cells in vitro.
Kosalec I, Safranić A, Pepeljnjak S, Bacun-Druzina V, Ramić S, Kopjar N. Kosalec I, et al. Basic Clin Pharmacol Toxicol. 2008 May;102(5):443-52. doi: 10.1111/j.1742-7843.2007.00204.x. Epub 2008 Jan 30. Basic Clin Pharmacol Toxicol. 2008. PMID: 18248512 Free article.
The results obtained suggest cytotoxic, cytostatic and genotoxic effects of the tryptophol treatment in vitro that were mainly dose-dependent. The type and the extent of DNA lesions detected in tryptophol-treated samples indicate the possibility that observed damage …
The results obtained suggest cytotoxic, cytostatic and genotoxic effects of the tryptophol treatment in vitro that were mainly dose-d …
238 results