The selectivity of Vibrio cholerae H-NOX for gaseous ligands follows the "sliding scale rule" hypothesis. Ligand interactions with both ferrous and ferric Vc H-NOX.
Wu G, Liu W, Berka V, Tsai AL.
Wu G, et al. Among authors: tsai al.
Biochemistry. 2013 Dec 31;52(52):9432-46. doi: 10.1021/bi401408x. Epub 2013 Dec 18.
Biochemistry. 2013.
PMID: 24351060
Free PMC article.
Similar to sGC, Vc H-NOX binds strongly to NO and CO with affinities of 0.27 nM and 0.77 muM, respectively, but weakly to O2. When positioned on a "sliding scale" plot [Tsai, A.-l., et al. (2012) Biochemistry 51, 172-186], the line connecting log K(D)(NO) and log K( …
Similar to sGC, Vc H-NOX binds strongly to NO and CO with affinities of 0.27 nM and 0.77 muM, respectively, but weakly to O2. When positione …