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The selectivity of Vibrio cholerae H-NOX for gaseous ligands follows the "sliding scale rule" hypothesis. Ligand interactions with both ferrous and ferric Vc H-NOX.
Wu G, Liu W, Berka V, Tsai AL. Wu G, et al. Among authors: tsai al. Biochemistry. 2013 Dec 31;52(52):9432-46. doi: 10.1021/bi401408x. Epub 2013 Dec 18. Biochemistry. 2013. PMID: 24351060 Free PMC article.
Similar to sGC, Vc H-NOX binds strongly to NO and CO with affinities of 0.27 nM and 0.77 muM, respectively, but weakly to O2. When positioned on a "sliding scale" plot [Tsai, A.-l., et al. (2012) Biochemistry 51, 172-186], the line connecting log K(D)(NO) and log K( …
Similar to sGC, Vc H-NOX binds strongly to NO and CO with affinities of 0.27 nM and 0.77 muM, respectively, but weakly to O2. When positione …
H-NOX from Clostridium botulinum, like H-NOX from Thermoanaerobacter tengcongensis, Binds Oxygen but with a Less Stable Oxyferrous Heme Intermediate.
Wu G, Liu W, Berka V, Tsai AL. Wu G, et al. Among authors: tsai al. Biochemistry. 2015 Dec 8;54(48):7098-109. doi: 10.1021/acs.biochem.5b00994. Epub 2015 Nov 25. Biochemistry. 2015. PMID: 26574914 Free PMC article.
Heme nitric oxide/oxygen binding protein isolated from the obligate anaerobe Clostridium botulinum (Cb H-NOX) was previously reported to bind NO with a femtomolar K(D) (Nioche, P. et al. Science 2004, 306, 1550-1553). On the other hand, no oxyferrous Cb H-NOX was observed …
Heme nitric oxide/oxygen binding protein isolated from the obligate anaerobe Clostridium botulinum (Cb H-NOX) was previously reported to bin …
199 results