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Page 1
AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma.
Basili I, Bufalieri F, Conenna M, Navacci S, Li YR, Torrejon J, Bernardi F, Lospinoso Severini L, Marsaud V, Cancila G, Bourmeau G, Yu H, Lo Re V, Talbot J, Adabbo G, Di Pinto A, Agnoli F, Giovannini D, Leonardi S, Bordone R, Petroni M, Souphron J, Blauwblomme T, Beccaria K, Dufour C, D'Angelo L, De Smaele E, Canettieri G, Giannini G, Fimia GM, Maroder M, Guardavaccaro D, Pazzaglia S, Tsai JW, Infante P, Ayrault O, Di Marcotullio L. Basili I, et al. Among authors: tsai jw. Dev Cell. 2026 May 13;61(5):1111-1126.e9. doi: 10.1016/j.devcel.2026.03.008. Epub 2026 Apr 13. Dev Cell. 2026. PMID: 41980781 Free article.
FOXR2-activated CNS neuroblastoma: Characterized by variable structural disruption of the FOXR2 regulatory region, recurrent copy number alterations, and elevated FOXR2 expression.
Ji J, Yellapantula V, Xu D, Estrine D, Markowitz A, Han J, Ma K, Fong C, Hawes D, Margol A, O'Halloran K, Robison NJ, Biegel JA, Cotter JA, Raca G, Tsai JW. Ji J, et al. Among authors: tsai jw. Neurooncol Pediatr. 2026 Mar 19;2(2):wuag014. doi: 10.1093/neuped/wuag014. eCollection 2026 Apr. Neurooncol Pediatr. 2026. PMID: 41978643 Free PMC article.
Epilepsy-associated FOXJ3 variants link a transcriptional program of the PTEN-mTOR pathway to neuronal specification and cortical lamination.
Cheng HY, Liu C, Nien CW, Huang HC, Zhao HJ, Nian FS, Chen C, Custodio HM, Sisodiya SM, Lu C, Chen HH, Hsu CS, Pi WC, Chu CC, Hsu JS, Chen PL, Chang FP, Tung CY, Chou SJ, Alavi S, Houlden H, Chen WY, Liu YT, Hou PS, Tsai JW. Cheng HY, et al. Among authors: tsai jw. Nat Commun. 2026 Mar 9;17(1):1815. doi: 10.1038/s41467-026-69241-2. Nat Commun. 2026. PMID: 41803108 Free PMC article.
Oncolytic adenoviral infection of chordoma achieves treatment efficacy associated with immunologic response and tumor microenvironmental alteration.
Wu X, Ledbetter D, Tsai JW, Singh S, Gumin J, Fan X, Gillard AG, Shin DH, Jiang H, Zhao B, Ingram D, Akdemir K, Conley AP, Lazar AJ, Raza S, North R, Tatsui C, Lang FF, Wang WL, Rhines LD, Gomez-Manzano C, Fueyo J, Alvarez-Breckenridge C. Wu X, et al. Among authors: tsai jw. Neuro Oncol. 2026 Jun 1;28(6):1458-1473. doi: 10.1093/neuonc/noag045. Neuro Oncol. 2026. PMID: 41795831
205 results