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Heteroresistance to carbapenems in Acinetobacter baumannii.
Pournaras S, Ikonomidis A, Markogiannakis A, Maniatis AN, Tsakris A. Pournaras S, et al. J Antimicrob Chemother. 2005 Jun;55(6):1055-6. doi: 10.1093/jac/dki115. Epub 2005 Apr 11. J Antimicrob Chemother. 2005. PMID: 15824088 No abstract available.
First report of an NDM-1 metallo-β-lactamase-producing Acinetobacter baumannii clinical isolate in Greece.
Voulgari E, Politi L, Pitiriga V, Dendrinos J, Poulou A, Georgiadis G, Tsakris A. Voulgari E, et al. Int J Antimicrob Agents. 2016 Dec;48(6):761-762. doi: 10.1016/j.ijantimicag.2016.09.006. Epub 2016 Sep 29. Int J Antimicrob Agents. 2016. PMID: 27773496 No abstract available.
Heteroresistance to meropenem in carbapenem-susceptible Acinetobacter baumannii.
Ikonomidis A, Neou E, Gogou V, Vrioni G, Tsakris A, Pournaras S. Ikonomidis A, et al. J Clin Microbiol. 2009 Dec;47(12):4055-9. doi: 10.1128/JCM.00959-09. Epub 2009 Oct 14. J Clin Microbiol. 2009. PMID: 19828742 Free PMC article.
Dissemination of linezolid-dependent, linezolid-resistant Staphylococcus epidermidis clinical isolates belonging to CC5 in German hospitals.
Layer F, Vourli S, Karavasilis V, Strommenger B, Dafopoulou K, Tsakris A, Werner G, Pournaras S. Layer F, et al. J Antimicrob Chemother. 2018 May 1;73(5):1181-1184. doi: 10.1093/jac/dkx524. J Antimicrob Chemother. 2018. PMID: 29360979
It is plausible that this characteristic is inherent and provides a selective advantage to CC5 LRSE under linezolid pressure, contributing to their dissemination throughout hospitals in these countries....
It is plausible that this characteristic is inherent and provides a selective advantage to CC5 LRSE under linezolid pressure, contrib …
Evaluation of two automated systems for colistin susceptibility testing of carbapenem-resistant Acinetobacter baumannii clinical isolates.
Vourli S, Dafopoulou K, Vrioni G, Tsakris A, Pournaras S. Vourli S, et al. J Antimicrob Chemother. 2017 Sep 1;72(9):2528-2530. doi: 10.1093/jac/dkx186. J Antimicrob Chemother. 2017. PMID: 28605445
METHODS: A total of 117 single-patient CRAB isolates collected randomly during 2015 from distinct tertiary hospitals located throughout Greece were tested. ...CONCLUSIONS: Colistin resistance of A. baumannii is greatly underestimated by Phoenix100/Vitek2, potentiall …
METHODS: A total of 117 single-patient CRAB isolates collected randomly during 2015 from distinct tertiary hospitals located througho …
Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in Greece: an extended review (2000-2015).
Karampatakis T, Antachopoulos C, Tsakris A, Roilides E. Karampatakis T, et al. Future Microbiol. 2017 Jul;12:801-815. doi: 10.2217/fmb-2016-0200. Epub 2017 Jun 12. Future Microbiol. 2017. PMID: 28604100 Review.
CRAB initially emerged in 2000 and since then, carbapenemases still have a crucial role in CRAB appearance, except for a few cases resulting from efflux pump or outer-membrane protein mechanisms. OXA-type carbapenemases present the highest prevalence worldwide and b …
CRAB initially emerged in 2000 and since then, carbapenemases still have a crucial role in CRAB appearance, except for a few c …
Emergence of OXA-162 Carbapenemase- and DHA-1 AmpC Cephalosporinase-Producing Sequence Type 11 Klebsiella pneumoniae Causing Community-Onset Infection in Greece.
Voulgari E, Poulou A, Dimitroulia E, Politi L, Ranellou K, Gennimata V, Markou F, Pournaras S, Tsakris A. Voulgari E, et al. Antimicrob Agents Chemother. 2015 Dec 14;60(3):1862-4. doi: 10.1128/AAC.01514-15. Antimicrob Agents Chemother. 2015. PMID: 26666930 Free PMC article.
OXA-162 is a rare OXA-48 variant usually coexpressed with extended-spectrum β-lactamases. Here, we report the identification of the first OXA-162 carbapenemase-producing Klebsiella pneumoniae isolates, which coexpressed an AmpC cephalosporinase (DHA-1), retrieved from a
OXA-162 is a rare OXA-48 variant usually coexpressed with extended-spectrum β-lactamases. Here, we report the identification of the f …
The Balkan region: NDM-1-producing Klebsiella pneumoniae ST11 clonal strain causing outbreaks in Greece.
Voulgari E, Gartzonika C, Vrioni G, Politi L, Priavali E, Levidiotou-Stefanou S, Tsakris A. Voulgari E, et al. J Antimicrob Chemother. 2014 Aug;69(8):2091-7. doi: 10.1093/jac/dku105. Epub 2014 Apr 15. J Antimicrob Chemother. 2014. PMID: 24739146
The blaNDM-1 gene was located on a narrow host range IncFII-type plasmid, of ∼95 kb, flanked upstream by a non-truncated ISAba125 element and downstream by the bleMBL gene. Genotyping clustered all K. pneumoniae isolates into a single clonal type with one sub …
The blaNDM-1 gene was located on a narrow host range IncFII-type plasmid, of ∼95 kb, flanked upstream by a non-truncated ISAba …
Growth retardation, reduced invasiveness, and impaired colistin-mediated cell death associated with colistin resistance development in Acinetobacter baumannii.
Pournaras S, Poulou A, Dafopoulou K, Chabane YN, Kristo I, Makris D, Hardouin J, Cosette P, Tsakris A, Dé E. Pournaras S, et al. Antimicrob Agents Chemother. 2014;58(2):828-32. doi: 10.1128/AAC.01439-13. Epub 2013 Nov 18. Antimicrob Agents Chemother. 2014. PMID: 24247145 Free PMC article.
In particular, a Col(s) isolate identical to Ab299 was still invading the bloodstream 90 days after the colonization of this patient by Col(r) isolates. These observations indicate considerably lower invasiveness of A. baumannii clinical isolates following the devel …
In particular, a Col(s) isolate identical to Ab299 was still invading the bloodstream 90 days after the colonization of this patient …
Detection of a phylogenetically distinct IMP-type metallo-β-lactamase, IMP-35, in a CC235 Pseudomonas aeruginosa from the Dutch-German border region (Euregio).
Pournaras S, Köck R, Mossialos D, Mellmann A, Sakellaris V, Stathopoulos C, Friedrich AW, Tsakris A. Pournaras S, et al. J Antimicrob Chemother. 2013 Jun;68(6):1271-6. doi: 10.1093/jac/dkt004. Epub 2013 Jan 22. J Antimicrob Chemother. 2013. PMID: 23341129
OBJECTIVES: To characterize a highly divergent IMP-type metallo-β-lactamase (MBL) variant detected in a multidrug-resistant Pseudomonas aeruginosa clinical isolate. ...A phylogenetic tree was constructed for the new blaIMP variant. RESULTS: Isolate 1876 was p …
OBJECTIVES: To characterize a highly divergent IMP-type metallo-β-lactamase (MBL) variant detected in a multidrug-resistant Ps …
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