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TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts.
Bossen C, Cachero TG, Tardivel A, Ingold K, Willen L, Dobles M, Scott ML, Maquelin A, Belnoue E, Siegrist CA, Chevrier S, Acha-Orbea H, Leung H, Mackay F, Tschopp J, Schneider P. Bossen C, et al. Among authors: tschopp j. Blood. 2008 Feb 1;111(3):1004-12. doi: 10.1182/blood-2007-09-110874. Epub 2007 Oct 17. Blood. 2008. PMID: 17942754
NLRs join TLRs as innate sensors of pathogens.
Martinon F, Tschopp J. Martinon F, et al. Among authors: tschopp j. Trends Immunol. 2005 Aug;26(8):447-54. doi: 10.1016/j.it.2005.06.004. Trends Immunol. 2005. PMID: 15967716 Review.
611 results