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A role for mitochondria in NLRP3 inflammasome activation.
Zhou R, Yazdi AS, Menu P, Tschopp J. Zhou R, et al. Nature. 2011 Jan 13;469(7329):221-5. doi: 10.1038/nature09663. Epub 2010 Dec 1. Nature. 2011. PMID: 21124315
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway.
Menu P, Mayor A, Zhou R, Tardivel A, Ichijo H, Mori K, Tschopp J. Menu P, et al. Cell Death Dis. 2012 Jan 26;3(1):e261. doi: 10.1038/cddis.2011.132. Cell Death Dis. 2012. PMID: 22278288 Free PMC article.
NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant.
Besnard AG, Guillou N, Tschopp J, Erard F, Couillin I, Iwakura Y, Quesniaux V, Ryffel B, Togbe D. Besnard AG, et al. Allergy. 2011 Aug;66(8):1047-57. doi: 10.1111/j.1398-9995.2011.02586.x. Epub 2011 Mar 28. Allergy. 2011. PMID: 21443539
Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome.
Menu P, Pellegrin M, Aubert JF, Bouzourene K, Tardivel A, Mazzolai L, Tschopp J. Menu P, et al. Cell Death Dis. 2011 Mar 31;2(3):e137. doi: 10.1038/cddis.2011.18. Cell Death Dis. 2011. PMID: 21451572 Free PMC article.
The role of the inflammasome in nonmyeloid cells.
Yazdi AS, Drexler SK, Tschopp J. Yazdi AS, et al. J Clin Immunol. 2010 Sep;30(5):623-7. doi: 10.1007/s10875-010-9437-y. Epub 2010 Jun 27. J Clin Immunol. 2010. PMID: 20582456 Review.
The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.
Schweneker K, Gorka O, Schweneker M, Poeck H, Tschopp J, Peschel C, Ruland J, Gross O. Schweneker K, et al. Immunobiology. 2013 Apr;218(4):664-73. doi: 10.1016/j.imbio.2012.07.029. Epub 2012 Aug 7. Immunobiology. 2013. PMID: 22921586
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Vince JE, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, Mason K, Gross O, Ma S, Guarda G, Anderton H, Castillo R, Häcker G, Silke J, Tschopp J. Vince JE, et al. Immunity. 2012 Feb 24;36(2):215-27. doi: 10.1016/j.immuni.2012.01.012. Immunity. 2012. PMID: 22365665
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β.
Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, Couillin I, Tschopp J. Yazdi AS, et al. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19449-54. doi: 10.1073/pnas.1008155107. Epub 2010 Oct 25. Proc Natl Acad Sci U S A. 2010. PMID: 20974980 Free PMC article.
Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages.
McCoy AJ, Koizumi Y, Toma C, Higa N, Dixit V, Taniguchi S, Tschopp J, Suzuki T. McCoy AJ, et al. Eur J Immunol. 2010 Oct;40(10):2797-803. doi: 10.1002/eji.201040490. Eur J Immunol. 2010. PMID: 20722078
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